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Abamax (Amitriptyline)

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Abamax is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine. Abamax is normally taken before bedtime because it can make you feel sleepy.

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Also known as: Amitriptyline


Abamax (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Abamax is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Abamax dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Abamax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Abamax if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Abamax if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Abamax is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Abamax is not approved for use by anyone younger than 12 years old.

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Progressive hyperinsulinaemia associated with advancing pregnancy was confirmed, together with evidence of a decreased sensitivity to insulin at a cellular level. Several studies have suggested an association between lipids or lipoproteins and depression, but findings are contradictory. We show that gametocyte rings are detected in the peripheral blood immediately following establishment of asexual infections-without the need for triggers such as high-density asexual parasitemia or drug treatment. We recorded the responses of single FEF neurons in monkeys trained to remember cued locations in order to detect changes in targets embedded among distracters in a task that did not involve saccades. They are also apt to confirm diagnostic conjectures and may help to adapt the therapeutic measures to the special situation. Voltammetry in room temperature ionic liquids: comparisons and contrasts with conventional electrochemical solvents. These data may be useful to slowly release pH-sensitive PLGA-encapsulated bioactive substances and provide a general framework for predicting partitioning behavior of degradation products in biodegradable polymers.

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The results show that trichiasis continues to affect elderly Aboriginal people, especially those from Halls Creek Shire. To evaluate the safety and complications of small-incision lenticule extraction (SMILE). CMR techniques, however, are not suitable to specifically detect myocardial viral infections. Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription. Patient recruitment methods to evaluate treatment decision making for localized prostate cancer. In an independent validation dataset of 4,836 AMI patients from Manitoba, the ROC areas were 0.77 and 0.78, respectively. He also argued that research in the field was largely flawed by confusion over the difference between things said about caring and the act of caring itself. Since quiescent NSCs in the normal adult spinal cord will proliferate and differentiate actively into neural cells after traumatic injury, we proposed that BMPs can regulate cellular components by controlling NSC differentiation. No evidence was found for a relationship between the compartment or stage of the prolapse and the presence of OAB symptoms. In some areas, irregular and small vessels proliferated markedly, while in others, pleomorphic and atypical tumor cells forming irregular vascular structures were predominant.

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Infective endocarditis complicated by aortic dissection and aorto-right ventricular fistula. A rare diaphragma sellae meningioma presenting only with signs of hypopituitarism occurred in a 54-year-old male. Patient was successfully treated with nutritional treatment and pancreatic enzymes. Weight gain (more than 2 kg) was strongly related to an increased risk for hypertension and hypercholesterolemia after being adjusted for possible confounding factors. Whereas heparin functions as an antithrombotic agent by promoting antithrombin III-based inhibition of thrombin and factor Xa, there is less appreciation for the combination behavior with small-molecule, direct inhibitors of these proteases. Additional toxicity studies are needed to establish the potency and range of toxic responses to mixtures of PAHs that fish encounter in the environment. The antalgic efficacy of chronic motor cortex stimulation is related to sensory changes in the painful zone. Information of the lifestyles and presence of metabolic syndrome factors was obtained.

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One of the latter two patients had cerebral damage during prolonged resuscitation and experienced repeated epileptic spells until he died unexpectedly. Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers. Silicon nanotubes (SiNTs) are compatible with Si-based semiconductor technology. Our data show that a single-nucleotide polymorphism (SNP) mutation in the GL4 gene resulted in a premature stop codon and led to small seeds and loss of seed shattering during African rice domestication. To evaluate the anatomy of the sphenoid ostium (SO), which has so far only been investigated with the aid of two-dimensional computed tomography (CT) or using a cadaver, from a new point of view through the use of 3D CT for the first time. The ATR-FTIR spectra indicated the presence of different types of biopolymers on two strains of bacteria. The structure proposed for the adduct initially formed on the enzyme is structure VII, Scheme II.

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The visceral nervous system as a mediator of psychosocial risk factors: therapeutic implications of its specific organization. Physical and biological treatments of polyethylene-rice starch plastic films. Cigarette smoking and associated health risks among students at five universities. It was found that OC had a beneficial effect on the premenstrual tension symptoms (PMT) in all age groups except in the youngest group (18 years), in which the tendency was rather the opposite. A previously healthy 3-year-old Japanese boy had a brief convulsion after fever for 3days, and then had conscious disturbance and parotitis. Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins. Misoprostol reduced urea-N synthesis rate (during fasting and in response to alanine), resulting in a positive nitrogen exchange. The main outcome measure was the odds ratio (OR) of ON among SLE patients. Differing views of its potential for producing dependence are discussed.

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One hundred thirty women with clinically and surgically diagnosed uterine leiomyomas and 139 population controls. Similar results were obtained with the fusion of Caf1 to hIL-1beta receptor antagonist or to human granulocyte-macrophage colony-stimulating factor. Primary diffuse cerebral leptomeningeal atypical teratoid rhabdoid tumor: report of the first case. Despite extensive studies in understanding the pathophysiology of GVHD, its pathogenesis remains unclear. The commercial ELISA, based on a monoclonal antibody to fathead minnow vtg, was compared to an ELISA that utilizes a fathead minnow polyclonal antibody, which has been used extensively in our lab and others for several years. Regional distribution of blood flow in calf muscles of rat during passive stretch and sustained contraction. The pelvis, an angulated upper segment of the ureter and the lower anterior renal segmental vessels entangle to produce hydronephrosis. Suppression of excluded-volume exponents in shear flow of dilute polymer solutions.

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Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls. Also, unlike other boosting methods that are only effective on a handful of datasets, tBRLPBoost works well on a variety of datasets. This descriptive study may be a useful starting point for further epidemiological studies of pain in the African context. To analyse the content of matrix MMP-2 and MMP-9 and their tissue inhibitor (TIMP-1) in blood serum and synovial fluid in various embodiments of juvenile arthritis in children. Epigenetic modifications of histones and regulation of chromatin structure have been implicated in regulation of virulence gene families in P. Three horses were considered mechanically lame and are in use with reduced expectations. The apolipoprotein E-dependent low density lipoprotein cholesteryl ester selective uptake pathway in murine adrenocortical cells involves chondroitin sulfate proteoglycans and an alpha 2-macroglobulin receptor. To determine how terminal differentiation and lactation influenced expression of intermediate filaments in breast epithelial cells, we used Western blot analysis to measure the levels of vimentin, alpha-smooth muscle actin, keratin 14, and keratin 18 in the resting and lactating breast. Psychological abuse and posttraumatic stress disorder in battered women: examining the roles of shame and guilt.

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The effect of an oral contraceptive on tests of thyroid function. PED is a measure of the responsiveness of the quantity demanded of goods or services to changes in price. This review highlights recent contributions to our understanding of chronic kidney disease outcomes in US Asians and Pacific Islanders. Erythrocyte membrane phospholipid composition closest reflects that of neuronal membranes. Development of a single-code/default coding strategy in pigeons. Our results show that msi-1 mediates the posttranscriptional regulation of tau expression by T3. State Boards of Nursing and scope of practice of registered nurses performing complementary therapies. Supplementation with rice bran increased the availability of energy and long-chain fatty acids, but amino acids then became the limiting factor. Fluorescein angioscopy demonstrated leaks beneath the serous retinal detachments in one.

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On the basis of the identified signature nucleotides, we designed polymerase chain reaction primer sets which (i) amplify all spirochete species associated with Lyme disease and (ii) differentiate between these species. Uterine nuclear suspension or nuclear KCl (0.5 M) extract from control and progesterone-treated (30 min or 2h) hamsters were incubated at 37 C for 0, 15, or 30 min in Tris-glycerol buffer. Human metapneumovirus (HMPV) was the predominant virus detected in 25.7 per cent children followed by influenza A (H1N1)pdm09, human rhinovirus (HRV) and human adenovirus (HAdV) in 19.9, 11.0 and 8.8 per cent children, respectively. Using quantitative RT-PCR, ELISA and immunohistochemistry we found that IL-13 and IL-15 mRNA and protein are expressed in control endometrium throughout the menstrual cycle and in RSA (cycle days 21-23) with peak expression detected immediately after and prior to onset of menses, and two distinct periods corresponding to late proliferative and the early-mid secretory phases, respectively. In one species of bushcricket, the mating system can be reversed by resource manipulation. The purified gp26 did not have killer activity, suggesting that further processing is necessary for acquisition of this activity. All other transthoracic results are not useful for ruling out IE, and subsequent TEE is almost always required. In turn, hypoxia was only observed when MG was combined (HFDMG group), being associated with impaired activation of the insulin receptor (Tyr1163), glucose intolerance and systemic and muscle insulin resistance. Secondary end points were primary assisted patency, secondary patency, technical success, major amputation, and mortality. Ion-molecule surface reactions induced by slow (5-20 eV) electrons.

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Fluid management and postoperative respiratory disturbances in patients with transthoracic esophagectomy for carcinoma. This new technology shows promise for the development of antiadhesion therapies against bacterial pathogens. There is a quite considerable percentage of urocultures that lead to a change in approach to therapy, although most of the patients had linked risk factors and/or did not receive empirical antibiotic treatment. The treatment strategies have certain limitations for female ACS patients. The effects of FXIII on clot formation and stability were examined using a thromboelastometry assay and blood samples collected from six patients with severe hemophilia A. Nine patients with Parkinson disease, 5 with progressive supranuclear palsy, and 6 with corticobasal syndrome underwent 3T MR imaging along with 12 matched, asymptomatic volunteers by using a protocol that included volumetric T1 and diffusion tensor imaging. The ABL kinase inhibitor imatinib has been used as front-line therapy for Philadelphia-positive chronic myeloid leukemia. Rapid purification of a high molecular weight human brain protein by chromatography on controlled pore glass.

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To evaluate the efficiency of self-complementary adeno-associated virus (scAAV)-mediated gene expression of green fluorescent protein (GFP) or the allotopic human ND4 subunit of complex I in ganglion cells of the primate retina. A series of mirror image (ent) forms of prostaglandins F2 and E2 have been compared for potency in a hamster antifertility test. Alexitimia patients have harmful behavioral habits (smoking, alcohol abuse) two times more precose tablets cost frequently than patients free of alexitimia. Continuous venovenous filtration with subsequential administration of sodium benzoate and l-arginine was started to eliminate blood ammonia. These combined data support the involvement of miR-185 and its down-stream pathways in schizophrenia.

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The presence of the VSV-G-encoding plasmid not only increased the number of mice displaying anti-Gag-specific cytotoxic response but also increased the efficiency of specific lysis. Identification of the infecting organism is critical to the successful management of deep prosthetic joint infections about the hip and the knee. FTY720 prevents chronic rejection of rat heterotopic cardiac allografts. We report a 63 year-old man that developed neuropsychological disturbances with hypersexuality as a prominent feature, disinhibition and moderate memory loss, hypersomnia and irritability after a bilateral paramedian thalamic infarction. Evaluation and application of the fluorochrome stain for microscopic detection of mycobacteria in clinical specimens. The increase in the proportion of larger particles of VLDL occurs due to an increase in the levels of the larger subclasses concomitantly with a reduction in the smaller particles. Effect of music and auditory stimuli on secretory immunoglobulin A (IgA).

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Predicting short term response to anti-inflammatory therapy in young children with asthma. Anomalous inelastic scattering of slow electrons in a vacuum near the surface of a polar dielectric or semiconductor. Findings that root traits are motrin peds dosage largely species dependent, with the exception of root tissue density, are discussed in the context of current literature on root trait variation, interactions with symbionts and recent progress in standardization of methods for quantifying root traits. Spatially localized stress fields produced by instrumented, sharp indentation probes are a route to testing the mechanical properties of materials at the smallest length scales. Finally, estimates of visual acuity based on the CS cards were consistent with those provided by the TAC (although CS-based estimates were generally lower overall). Is the ratio of pleural mesothelioma mortality to pleural cancer mortality approximately unity for Italy?. The value of this information to teachers within the two disciplines and to the wider dental community is briefly discussed. Production of Sporotrichum thermophile xylanase by solid state fermentation utilizing deoiled Jatropha curcas seed cake and its application in xylooligosachharide synthesis. As such, regional anesthesia should likely be the favored anesthetic modality for patients undergoing MLEA. One parameter, the predilection for rounding of cells at metaphase, was studied using time-lapse cinephotomicrography and fixed, stained preparations.

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Besides emphasizing the importance of the early interaction phase for subsequent reproductive processes, the gained knowledge might further be implemented for in vitro applications as well. To observe the effect of icariin on human periodontal ligament cells (hPDLCs) differentiation to osteoblast gene expression. These effects were not observed in the superficial laminae of thoracic dorsal horns. First, several compounds were identified which are equally potent as inhibitors of human keratinocyte growth as the antipsoriatic agent anthralin. Our results supported the findings of some rheumatoid arthritis susceptibility genes identified in the literature. The aim of this study was to determine the efficacy and safety profile of gemcitabine plus cisplatin in patients with immunohistochemically proven unresectable cholangiocarcinoma.

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