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Abzole (Acetazolamide)
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Abzole

Abzole is the only carbonic anhydrase inhibitor with significant diuretic effects. It is readily absorbed and undergoes renal elimination by tubular secretion. Its administration is ordinarily marked by a brisk alkaline diuresis.

Other names for this medication:
Abzole, Aceact, Acetamide, Acetamin, Acetariv, Acetazolamide, Actamid, Actamide, Actazid, Antilep, Axytex, Carbadac, Iopar, Mazetol, Mezapin, Synomax, Tegrital, Zolamide

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Also known as: Acetazolamide

Description

Abzole reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Abzole is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Abzole is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Abzole is also used to treat certain types of seizures, and to treat or prevent altitude sickness.

Dosage

Abzole is available in tablets. The dosage depends on the disease and its prescribed treatmen. Glaucoma treatment: 250 mg to 1 gram per 24 hours in 2 or more smaller doses. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 mg every 4 hours or, in some cases, 250 mg twice a day. Epilepsy treatment: The daily dosage is 8 to 30 mg per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 mg per day. Congestive Heart Failure treatment: The usual dosage is 250 mg to 375 mg per day or 5 mg per 2.2 pounds of body weight, taken in the morning. Abzole can be used by children. If you want to achieve most effective results do not stop taking Abzole suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Abzole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Abzole Sequels may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid exposure to sunlight or tanning beds. Abzole Sequels can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Organ transplantation places patients at risk for tuberculosis (TB), which constitutes a challenge to physicians due to its atypical and extrapulmonary presentations, complicated treatment issues, and high morbidity and mortality. Microtubules and 10 nm-filaments appear to be involved in the functions of the retinal pigment epithelium (RPE). Coenzyme Q10 is involved in the synthesis of ATP and hence is useful in preventing cellular damage during ischaemia-reperfusion injury. Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis. Immunoregulatory cytokines gene polymorphisms in Egyptian patients affected with acquired aplastic anemia. Age-related macular degeneration (AMD) is a leading cause of legal blindness in the elderly in the industrialized world and the third major cause of blindness around the globe. Immunoneutralizing glucagon in critically ill mice only transiently affected glucose and lipid metabolism, did not affect muscle wasting, but drastically suppressed markers of hepatic amino acid catabolism and reversed the illness-induced hypoaminoacidemia. Hyperinsulinemia and insulin resistance in hypertension: differential effects of antihypertensive agents. The idea that it is the same as death of the whole person has been tested in medical research and legally, which has provided evidence to support the withdrawal of advanced medical treatment and for discussion of organ donation. The predictive accuracy of the demographic model improves when it is extended with diagnostic information from prior hospitalizations (DCGs).

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