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The HERMIONE study will evaluate the efficacy and safety of MM-302 plus trastuzumab in patients with refractory HER2-positive advanced/metastatic breast cancer for whom there are no standard of care therapies with a proven survival advantage. This prospective before-after study was intended to investigate the effect of Bio-Kil on reducing environmental bacterial burden and healthcare-associated infections (HAIs) in intensive care units (ICUs) at the Municipal Wan-Fang Hospital, Taipei, Taiwan in 2014. Hypoxia promotes aggressiveness, angiogenesis and resistance in glioma. Problems associated with this condition and their management is discussed. p73 Overexpression increases VEGF and reduces thrombospondin-1 production: implications for tumor angiogenesis.
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