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Acquire (Levofloxacin)

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Acquire is used to treat bacterial infections in many different parts of the body. It is also used to prevent an anthrax infection after a person has been exposed to anthrax. This medicine is also used to treat and prevent plague (including pneumonic and septicemic plague).

Other names for this medication:
Acquire, Armolev, Corvox, Cravit, Elequine, Evonex, Farlev, Lailixin, Laiwoxing, Lefos, Letab, Levin, Levobact, Levocin, Levodak, Levoflox, Levofloxacina, Levofloxacinum, Levonix, Levoprolin, Levoquinox, Levotac, Levoxacin, Levoxal, Levoxetina, Levoxin, Levozine, Lexacin, Loxin, Medibiox, Mosardal, Nevotek, Oftaquix, Olcin, Potant, Prolecin, Quinolev, Recamicina, Reskuin, Resquin, Rinvox, Tavanic, Teraquin, Urilev, Voflaxin, Volox, Yaxinbituo

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Also known as: Levofloxacin


To reduce the development of drug-resistant bacteria and maintain the effectiveness of Acquire and other antibacterial drugs, Acquire should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Acquire Tablets/Injection and Oral Solution are indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed in this section. Acquire Injection is indicated when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).


Take Acquire exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take this medicine with water, at the same time each day. Drink extra fluids to keep your kidneys working properly while taking this medicine.

You may take Acquire tablets with or without food.

Take levofloxacin oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Acquire will not treat a viral infection such as the flu or a common cold.

Do not share Acquire with another person.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use levofloxacin.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Acquire dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acquire are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, ofloxacin, norfloxacin, and others).

Levofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop using levofloxacin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).

Tell your doctor if you have ever had:

tendon problems, bone problems, arthritis or other joint problems (especially in children); blood circulation problems, aneurysm, narrowing or hardening of the arteries; heart problems, high blood pressure; a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome; diabetes; a muscle or nerve disorder, such as myasthenia gravis; liver disease; kidney disease; seizures or epilepsy; a head injury or brain tumor; long QT syndrome (in you or a family member); or low levels of potassium in your blood (hypokalemia).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

You should not breast-feed while using this medicine.

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PEP adherence rates in Tel Aviv were significantly higher than previously reported. Accordingly, 3-beta-acetoxy-tirucallic acid did not inhibit the activity of Akt1 lacking the pleckstrin homology domain. Therapeutic implications of diazepam in patients with elevated left ventricular filling pressure. The automatic quantification has a similar ability to assign perfusion abnormalities to the diseased coronary artery as compared to an expert panel. The necessity of radical excision and gentle handling of the tumor during the operation are reemphasized. In this study, we will discuss the data suggesting the existence of CSC in lung tumors and the potential clinical utility of CSCs as prognostic markers or cellular targets of new therapeutic strategies.

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In this regard, the neuropeptide hormone, oxytocin, is thought to underlie social cognitions and behaviors that promote social affiliation. One of the two Sp1 sites essential for basal promoter activity was identified as critical for the TSA effect, but the binding of Sp1/Sp3 to this site remained unchanged in the absence or presence of TSA. Effect of n-propyl substituents on the emission properties of blue phosphorescent iridium(iii) complexes. More interestingly, the intensity of applied water stress was correlated with increased production of H2O2 and O2 (-) and elevated activity of PM NADPH oxidase, a key enzyme of reactive oxygen species generation in plants. The calcareous corpuscles were formed in a cell which we named calcareous corpuscle forming cell. Nuclei were counted in intestinal cells examined in serial sections of larvae recovered from a great heron and a fish, in which a mean of 1.6 nuclei/cell was found, corresponding to data published for Gnathostoma binucleatum. In most bacteria, ACC is composed of four subunits encoded by accA, accB, accC, and accD. The interactions of Eu(III) chelates with the silver rods were also proven by extremely reduced lifetime.

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A literature search revealed that this type of injury has not been reported previously. Previously unknown 4,5-epoxy-N-acetyl-sphingosine (1) was synthesized by epoxidation of N-acetyl-sphingosine with 1,1-dimethyldioxirane. They provide a new aid to the classification of disorders involving abnormal growth of the arms. The distribution of thiamine-immunoreactive structures was studied in the brain of the monkey using an indirect immunoperoxidase technique. Effect of Zn impurities on the normal-state Hall angle in single-crystal YBa2Cu3-xZnxO7- delta. These methods have been applied to the titanium dioxide (110) surface, using first principles density functional theory. Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review).

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First, this patient lacked any of the high-risk features of myelodysplastic syndrome that typically portend transformation. The impact of current nighttime staffing requires further evaluation with respect to patient outcomes. Cells from photosensitive TTD patients show reduced DNA repair levels similar to those found in xeroderma pigmentosum. He was diagnosed as having spinocerebellar ataxia at the age of 46. Solidification of floating organic droplet in dispersive liquid-liquid microextraction as a green analytical tool.

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16 patients with ureteropelvic junction (UPJ) obstruction treated by antegrade endopyelotomy were evaluated. Moreover, troponin I levels identify additional groups of patients at increased risk of death not so identified by measuring CK-MB values. Using immunocytochemistry and confocal imaging we were able to resolve individual triads within the cone pedicles by light microscopy. This may explain the more rapid disease progression for subtype D compared with subtype A. Hyperthymic temperament typology seemed to be highly protective for HUD and, though a bit less, for AUD patients, and was a typical feature of healthy controls. Wavefront data in the form of Zernike polynomial coefficients from several VISX US Investigational Device Exemption studies were used to calculate the spherocylindrical distance correction using four methods: full pupil second order, central curvature, reduced aperture, and 4-mm pupil.

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Ivermectin residues had no effect on the survival of sexually mature beetles, but reduced the fecundity of O taurus. Some other general effects in the mice and some aspects of the structure-activity relationship are discussed. Phosphorus in SS was suggested to be more easily bioavailable in the urban river than the rivers in agricultural areas. The paper presents a theoretical derivation of the photon fluence simulation efficiency in photon beam treatment head simulations without and with bremsstrahlung splitting. Our aim was to test the hypothesis that hyperbaric oxygen therapy may restore cardiac neural regulation dysfunction in diabetic individuals with foot complications. A survey was conducted to determine if inactive female medical technologists wish to reactivate, what degree of retraining they feel necessary to do so, and their willingness to pay for such experience. Inaccurate recall persisted across tests for both immediate and delayed recall and increased across tests for immediate recall.

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Mean levels of pH and duration of hyperacidity in the body and an antral part of the stomach, duration of DGR, pH in the body and antral part of the stomach depending on DGR severity were studied. This review will provide a general picture of the physiological and pathophysiological roles of the TRPV1 channel and of its structural, pharmacological and biophysical properties. Inhibitory effects of serotonin on transient outward potassium current in rat ventricular myocytes. Experimental flow and perfusion measurements in the animal model with magnetic resonance tomography. A cohort of 504 post-menopausal women was recruited from primary care in South West UK. In the control experiments, the mean peak acid response occurred 45 min after feeding and the mean peak gastrin concentration 15 min after feeding. Inhibition of inflammatory cytokines may have therapeutic effects in diabetic retinopathy (DR). Ingestion of killed cells of a highly cariogenic strain of Streptococcus mutans induced specific antibodies in both saliva and milk but not in serum of gnotobiotic rats. Triage performance of Swedish physicians using the ATLS algorithm in a simulated mass casualty incident: a prospective cross-sectional survey. Cisplatin (CP) therapy as the most common potent chemotherapeutic process is accompanied by nephrotoxicity.

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In response to prednisone therapy, his insulin requirement decreased, but the total and free insulin concentrations increased as insulin antibody measured as the maximal insulin-binding capacity of plasma remained unchanged. Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. Successful hemodynamic repair of left ventricular-aortic discontinuity complicating bacterial endocarditis in 2 patients was achieved using a composite valve-woven Dacron tube graft. We conclude that the rapid upregulation of human alphabetagamma-ENaC activity in oocytes by external 8-pCPT-cGMP and 4-chlorothiolphenol-cAMP depends on the para-chlorophenylthiol and the hydroxy groups, and 8-pCPT-cGMP may serve as a novel ENaC ligand in addition to activating PKG signal. Physician scarcity is associated with further scarcity in US communities, while scarcity is associated with recovery from scarcity in Japanese communities.

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Although thymine glycol pairs with its cognate base and is not mutagenic it significantly distorts the DNA molecule and is a lethal lesion. Male rat urine affects the behaviour and sexual response of female rats, leading to the proposal that rodent urinary proteins are responsible for binding pheromones and their subsequent release from drying urine. This result indicates the need to control for the coarse-level categorial organization when performing studies on higher-level processes related to the retrieval of semantic information. Because of its rarity and unremarkable clinical presentation, a timely diagnosis is very challenging. Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription. One of the main objectives of the meeting was to identify effective strategies which could feasibly be implemented at establishments. Electrophoretic mobility and deformation of large DNA during gel electrophoresis.

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While some bees solely collect pollen, others only collect nectar. When immunized with trinitrophenyl-keyhole limpet hemocyanin, dbh-/- mice produced less Th1 cytokine-dependent-IgG2a antitrinitrophenyl antibody. Vestibulo-ocular reflex in the dark had a maximum gain of 0.6 (1.0 in normal animals). Smoking cessation during pregnancy is desirable to improve health outcomes in offspring.:. Histopathological examination of the placenta is the gold standard for evaluating antenatal inflammatory processes that might influence fetal development. The levels of PAc gene and protein expression were markedly decreased by ultrasonic stimulation for 20 min. Our data have shown 23 RAPD patterns (A-W) distributed among the zithromax pill image 32 P.

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Increased awareness of these types of cases might improve the performance of thyroid fine-needle aspiration in clinical practice. We evaluated our method by applying it to fowl adenovirus isolates, catfish herpesvirus isolates, and largemouth bass ranavirus (iridovirus) from cell culture and lymphocystis disease virus (iridovirus) and avian poxvirus from tissue. An increase in cardiomyocyte levels of Mfn2 attenuated the DOX-induced increase in mitochondrial fission and prevented cardiomyocyte mitochondrial ROS production. Individuals attempting weight reduction have varying success when participating in the same intervention. The scheme allows for efficient computation of thermodynamic properties, including winding numbers and off-diagonal correlations, for systems of much greater size than that accessible to conventional PIMC simulations. Behavioral correlates of focal hippocampal x-irradiation in rats. Tolerance for nutrient imbalance in an intermittently feeding herbivorous cricket, the Wellington tree weta. Here, we describe a cDNA for a G protein-coupled diapause hormone receptor with seven transmembrane domains. Multilevel random effects models applied to daily diary data indicated that on pain days when children practiced their strategies, they had fewer health care contacts, fewer school absences, and less interference with household activities than on days when they did not practice.

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Surface interactions and applied-field effects in cholesteric helicoidal and blue phases. In trauma and inflammation, Ahsg is down-regulated and therefore considered a negative acute phase protein. Only the macrophage enriched fractions were found to cause stimulation. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by treatment with an anti-rat CD5 antibody (OX19). Behavior of radon in rooms and its use as indicator for ventilation measurements. (RQ2) What is the contribution of the literature in the development of hybrid materials in the field of orthopedic research?. Qualitative image analysis included morphology of the lateral ventricles (normal, parallel pattern colpocephaly), signal intensity changes of the fetal brain, interruption of the germinative matrix, agenesis of the corpus callosum (complete/partial) and associated malformations. Adenoviral overexpression of KLF2 inhibits the LPS-mediated induction of proinflammatory factors, cytokines, and chemokines and reduces phagocytosis. In all of them, pain significantly interfered with daily activities.

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Leptomeningeal metastasis from cervical adenosquamous carcinoma is extremely rare especially after radiotherapy for vertebral metastasis. PCR-CSGE is a highly sensitive and special assay for detecting single base mutation. Four male and four female patients with FHHNC and CLDN16 mutation, under long-standing HCT therapy (0.4-1.2 mg/kg, median 0.9 mg/kg, dose according to calciuria), aged 0.7-22.4 years, were included in a clinical study to investigate the effect of HCT on calciuria. Healthcare providers need to pay attention to the psychological vulnerability of caregivers to encourage a hopeful attitude. This then allows for effective diagnosis and management of foodborne outbreaks. The role of cyclic nucleotides and calcium in the relaxation produced by amrinone in rat aorta. A number of CFD studies, considering both forward and retrograde flow through valves, have been published. Ultrastructural analysis of chloroplast development suggested that clpP disruption also induced swelling of the thylakoid lumen in the meristem plastids and inhibition of etioplast development in the dark. An experimental study of cerebral circulation under the use of thyroid depressants. Infectious diseases in children admitted from a residential child care centre.

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A 10-year-old boy presented to the emergency department after being struck by a van while crossing the street. This study assessed their competencies in detecting malnourished children 5 years and below in Beledweyne. The relative strength of interaction depended on the number of amino acid units in the peptide, side chain bulk and electronic properties and hydrophobicity of the amino acids. The interactions between the forms of treatment appear to be more than merely additive, since each can enhance the effects of the other. Using an avidin-biotin technique with a polyclonal anti-human placental aromatase, we demonstrated the existence of aromatase in normal prostates of young men and BPH tissue from elderly men. Wireless, and to a lesser extent, wired pen-PDAs hold the potential to make web-based electronic medical records accessible from anywhere at any time. A retrospective analysis of all military casualties returning to the Walter Reed Army Medical Center and the National Naval Medical Center, Bethesda, Maryland, from April 2003 until April 2008 was performed.

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Aflatoxin Exposure During Pregnancy, Maternal Anemia, and Adverse Birth Outcomes. This effect was attributed to DNA-protein cross-linking, since the effect was reversed by treatment of the cell lysates with proteinase-K. This study sought to identify the modulating influence of extracardiac factors on persistent angina pectoris after myocardial infarction. Morbidity (complications), and quality-of-life were secondary outcomes. Predictability is possible only on a short-term basis, and unpredictability sets in over the long run. When the corresponding fragment of the Salmonella typhimurium chromosome was transferred to E. The fate of Trichophyton verrucosum in the guinea-pig organism conditioned by the route of its administration. The quantity of manganese on MOCS was determined by means of acid digestion analysis.

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Compared with wild-type mice, IL-1beta-/- mice were relatively resistant to induction of clinical experimental autoimmune myasthenia gravis (EAMG). We conducted a 10-month qualitative study (May 2010-February 2011) in a village in Punjab, Pakistan. Evolution of senescence: natural increase of populations displaying Gompertz- or power-law death rates and constant or age-dependent maternity rates. This microfluidic system enables us to control the bending of the thread and to enhance mixing between liquids having significantly different viscosities. Single- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects. This study identified factors associated with use of the emergency department for medical reasons among individuals with serious mental illness. Suspected colonic polypoid disease should be evaluated colonoscopically despite radiographic evidence of benignity. These cells were transplanted intraperitoneally into twitcher neonates. The dynamic nature of the ST-T segment in ischemic heart disease.

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In terms of blood pressure lowering, both HCTZ and chlorthalidone appear to be very effective. Also possibly influenced are micelle formation, intestinal health, breast milk jaundice, and the absorption of other nutrients. Lobeline and nicotine exerted a biphasic effect on GABA level: in small doses given 15 min before decapitation they decreased, and in higher doses and after longer time intervals they increased this level. Wound healing in horses is often complicated by wound infection, exuberant granulation tissue, and hypertrophic scars, especially when wounds are located on the limbs. Often you cannot be sure of the prognosis in spite of knowing the diagnosis. Although antibiotics have been reported to be effective for acute and prophylactic phases in several uncontrolled studies and non-steroidal anti-inflammatory drugs (NSAID) are used during exacerbations, clinical multicenter trials are still missing. We propose a new assay for the measurement of GAA by a simple CZE UV-detection without previous sample derivatization. pictures of atenolol 25 mg

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Physical transfer of data was not necessary, and turn-around-time was not increased. After briefly reviewing several popular dispersion estimation methods, this article describes a simulation study that compares them in terms of point estimation and the effect on the performance of tests for differential expression. Blood smears were obtained from 15 ostriches out of a group of 25 birds 4 and 2 days before and then 2 and propecia 1mg generic 4 days after translocation. Since intestinal blood flow is also, in part, supplied by the inferior mesenteric artery, it was of interest to determine the effect of the administration of furosemide on blood flow in this vessel. These sucrose isomers cannot be metabolized by plant cells and most other organisms and therefore are possibly advantageous for the pathogen. In contrast to the effect of the free drug, no toxic effects could be demonstrated after incubation with DNA-linked daunorubicin (100 microM) for 5 hours. The benign serrated architecture of the hyperplastic polyp has now been recognized in morphologically similar lesions with potential for transformation to colorectal carcinoma: the sessile serrated adenoma (SSA), traditional serrated adenoma (TSA), and mixed polyp.

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It is known that the vibration characteristics of the fingers and hand and the level of grip action interacts when operating a power tool. In March 2001, in response to concerns about increasing resistance to fluoroquinolone (FQ) antibiotics, the Ontario Drug Benefit (ODB) program limited reimbursement of FQs to ODB beneficiaries defined as high risk or in whom other therapies are not tolerated. Portal vein angioplasty has been successfully established for treatment of portal vein stenosis using mesenteric or percutaneous, transhepatic approaches. However, expanding our dataset to a larger number of extinct taxa with intermediate morphologies is necessary to exclude the possibility that the morphology of extant taxa is not dominated by convergence along long branches. The aim of this study was to survey cannabis users to determine whether they had intentionally substituted cannabis for prescription drugs.

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The patient recovered full weight bearing capability after a year. 49 of 50 newborn infants, when presented with a strong auditory stimulus, showed significant increases in EMG potential. Serum glucose, luteinizing hormone LH, follicle stimulating hormone FSH and thyrotropin TSH were not altered significantly. Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. Cystadenoma of the Rete Testis in a Patient With von Hippel-Lindau Disease. A similar acceleration of bone loss was also reported in aging CB2-deficient mice but found to be associated with enhanced bone turnover. Incubation of U937 cells with IFN-gamma sensitized these cells to apoptosis induced by tumor necrosis factor-alpha, agonistic CD95 antibody, and tumor necrosis factor-related apoptosis-inducing ligand. Large ATP-dependent proteolytic complexes carry out the majority of intracellular proteolysis. Harmonization of pathology quality assurance methods that minimize subjectivity and improve reproducibility among collections would facilitate research-relevant specimen selection by investigators and could facilitate information sharing in an integrated network approach to biobanking.

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However, certain insulators can show similar oscillations of the magnetization from quantization of the energies of electron states in filled bands. One cage had a wire floor and the other had a sand floor, but the cages either were on the same (low or elevated) or on different levels (one cage 40 cm higher than the other). The most common type of esophageal cancer in Southern Thailand is squamous cell carcinoma, as in other countries in Asia. The major alkaloid component was cytisine, with N-methylcytisine, anagyrine, and the fatty acid compositions were determined. Isolation and cultivation of blastocyst-derived stem cell lines from American mink (Mustela vison). Here cost of glucotrol xl we use quantitative genetic analyses to identify and estimate the shared genetic effects between molar size and trunk length in a pedigreed, breeding population of baboons housed at the Southwest National Primate Research Center. Therapeutic mirror interventions: an integrated review of the literature. The aim of this study is to describe mitral valve repair technique based on an anatomical and functional approach. Formation of a sigma complex as a hypothetical rate-determining step in the carcinogenic action of unsubstituted polycyclic aromatic hydrocarbons. The contribution of new therapies, somatostatin analogues and targeted therapies needs to be defined.

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