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Adapin (Doxepin)
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Adapin

Adapin works by slowing activity in the brain to allow sleep. This helps you relax and feel more energetic. It also helps you concentrate better and improves your quality of life. Take this medicine in the dose and duration as advised by your doctor.

Other names for this medication:
Adapin, Doxedep, Doxepin, Doxure, Neuro, Noctaderm, Silenor, Spectra

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Also known as: Doxepin

Description

Doxepin is used to treat anxiety or depression. It is also used to treat insomnia (trouble with sleeping).

Doxepin is a tricyclic antidepressant (TCA). It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain doxepin. It may not be specific to Adapin. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the Adapin® oral liquid or capsule once a day, you may take it at bedtime.

To use the Adapin® oral liquid:

Measure the dose with the calibrated dropper that comes with the medicine. Mix each dose with about one-half glass (4 ounces) of water, whole or skimmed milk, orange juice, grapefruit juice, tomato juice, prune juice, or pineapple juice. Do not mix this medicine with grape juice or carbonated beverages (soda pop). Mix the medicine just before taking the dose. Do not prepare it ahead of time.

To use the Silenor® tablet:

Do not take this medicine within 3 hours of a meal. It may not work as well, or it might make you sleepy the next day if you take it with or right after a meal. Take the tablet 30 minutes before going to bed, when you are ready to go to sleep. Do not take the medicine unless you can get a full night's sleep (7 to 8 hours). If you wake up too soon, you may feel drowsy from the medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or solution): For depression or anxiety: Adults and children 12 years of age and older—At first, 75 milligrams (mg) once a day or in divided doses during the day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg per day. Children younger than 12 years of age—Use is not recommended. For oral dosage form (tablets): For insomnia: Adults—6 milligrams (mg) once a day. Older adults—At first, 3 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Adapin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Adapin dosage information

Side effects

The most common side effects associated with Adapin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of doxepin capsules and solution for the treatment of depression and anxiety in children younger than 12 years of age. Safety and efficacy have not been established.

Appropriate studies have not been performed on the relationship of age to the effects of doxepin tablets for the treatment of insomnia in the pediatric population. Safety and efficacy have not been established.

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To determine the feasibility and efficacy of combination nonviral lipid-formulated murine interleukin 2 (mIL-2) and polymer-formulated murine interleukin 12 (mIL-12) gene therapy for head and neck squamous cell carcinoma (HNSCC) in a murine model. The analysis included 1893 women with epithelial ovarian cancer ascertained from three population-based studies. Of these, six were medial femoral condyle bone grafts, seven were skin flaps from the medial knee, and nine composite osteocutaneous or tendo-osteocutaneous flaps. Consequently, the rate of complications, especially hypoparathyroidism, has increased. This meta-analysis examines the effect of single-shot ISB on analgesic outcomes during the first 48 hours after shoulder surgery. The root projection into the sinus and the interruption of the sinus floor are indicative signs of root protrusion into the sinus on CBCT.

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