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Adipine (Nifedipine)
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Adipine

Adipine is used to treat hypertension (high blood pressure) and angina (chest pain). Adipine is in a class of drugs called calcium channel blockers. Adipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adipine OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Adipine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Adipine dosage information

Side effects

The most common side effects associated with Adipine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

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Analyzing the results confirmed that construction of hernia meshes made of PVDF could be an advantageous alternative to the commonly used materials due to an improved biostability. Transcatheter renal artery embolization: clinical applications and techniques. Threshold of degradation for frequency-distributed band-limited noise in continuous speech. Sensors that were able to maintain a midline position, high in the mediastinum, had the best signals. The purpose of this review is to briefly describe the physiologic stress induced by surgical intervention in the preterm, low birth weight patient with NEC and to provide a contemporary overview of available surgical management options for NEC. High-intensity focused ultrasound (HIFU) is a promising treatment method for many common cancers, including prostate cancer.

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Effect of vaccinia-activated macrophages on scrapie infection in hamsters. To study the clinical and investigative profile of subacute mountain sickness amongst Indian soldiers stationed at extreme altitude. Demonstration of LSD in body fluids with high performance liquid chromatography. Additional high speed operation, fast delay control, and wide range of operation wavelength make the present approach practical. The three main measurement methods that this review considers are the geometric method, the tendon excursion method and the direct load method. Cells were collected every 4 h in LD and DD, and RNA was isolated. In order to evaluate current folate status in the healthy Kazakh population, we screened serum folate and plasma HCY in 50 healthy Kazakh adults aged 20-65 years (KZH) and 60 healthy Japanese control subjects aged 27-65 years (JPN). Orthodontic anchorage without negative reciprocal influences on tooth position can be achieved by the use of immobile implants. The patients in one centre received a nasogastric tube and a transanastomotic feeding tube during the operation, while in the other centre only a nasogastric tube was used. These effects were larger when the reinforcer ratio was more extreme.

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The effect of gradual increment in rhG-CSF dose on stem cell yields in patients with multiple myeloma mobilized with intermediate dose cyclophosphamide plus rhG-CSF. This paper provides an overview of the effects of cryopreservation on obstetric outcome and child development. Pre-exposure to LPS led to impaired activation of both the pathways. Validation of sentinel node mapping in patients with colon cancer. Mechanical properties and bio-tribological behaviors of novel beta-Zr-type Zr-Al-Fe-Nb alloys for biomedical applications. A so-called gold standard of union or nonunion was determined by either surgical findings (for twenty-five patients who were operatively treated) or six months of clinical observation (for ten patients who had nonoperative treatment). The need for a reliable and convenient tool for automated sequence annotation is broadly recognized. Coordinated motor action is also shown to suppress random thermal noise on large time scales, the two-dimensional configuration that the system starts with thus remaining planar during the structural development. Three additional transcription units, namely spo0A, spoVG and the ytxGHI operon (also known as the csb40 operon), were found to be under the dual control of RelA and sigmaH in amino acid-starved cells, but many other sigmaH-dependent genes were not activated under these conditions.

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We discuss neural circuit mechanisms that underlie the generation and regulation of motor variability and consider the implications that this work has for our understanding of motor learning. Adenoviral vectors are highly efficient at transferring genes into cells and are broadly used in cancer gene therapy. Photodynamic therapy with 5-aminolevulinic acid in actinic cheilitis: an 18-month clinical and histological follow-up. Although these chronic lung diseases differ in their geoepidemiology and immunopathogenesis, emerging evidence suggest that organ-specific autoimmunity may underlie subphenotypes of COPD and IPF. Accumulating evidence has shown that microRNAs (miRNAs) are aberrantly expressed in human esophageal cancer and crucial to tumorigenesis.

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One hundred and twenty-nine patients from 10 general practices across London and the South Thames region who had experienced symptoms of fatigue for at least three months. 2-OH-A possesses significant mutagenic potential in living cells. Human-observer performance in several signal-known-exactly detection tasks is evaluated through psychophysical studies by using the two-alternative forced-choice method. Spike potentials and membrane properties of dorsal root ganglion cells in pigeons. Sensitivities of the computed trajectories to parameter variations permit more detailed attribution of uncertainties in the predictions to these low-level properties. In both the uncrossed (all elements in test and mask defined by either colour or luminance contrast) and crossed (equal mixtures of luminance and colour contrast in both test and mask) conditions, evidence of sub-threshold facilitation between test and mask was obtained.

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The essential factors for a good outcome include appropriate surgical indication, avoidance of aortic crossclamping and cardiac arrest, and unobstructed anastomosis between the superior and inferior venae cavae and the pulmonary artery. Fabrication of biomimetic superhydrophobic surface on engineering materials by a simple electroless galvanic deposition method. Traditional methods of nasopharyngectomy for the treatment of recurrent nasopharyngeal carcinoma carry considerable complications. Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers. mSRC-3-AS had no effect in either genotype, and SRC-3 knockout mice exhibited full receptivity. Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Although there is no clearly optimal first- or second-line chemotherapy regimen for thymic carcinoma, platinum-based chemotherapy has repeatedly been shown to be of benefit to patients with advanced thymic carcinoma. None of the subjects had a late increase in plasma radioactivity to suggest recirculation of radioiodide or buildup of iodoproteins. Furthermore, in Study 4, changes in state narcissism mediated changes in desire for fame and perceptions that others deserve help.

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Because of recent reports showing an increased risk for stroke following traumatic brain injury (TBI), we undertook a pilot study to investigate coated-platelet synthesis in veterans with TBI. It is well known that probiotics are helpful for specific disorders and different clinical studies have indicated that probiotics have special effects in cutaneous apparatus directly or indirectly that can be considerable from versatile aspects. University of East Anglia child health nursing lecturer Katie McGhee has responded to a letter published in International Airport Review. Moreover, we examined the role of SlCPI in signaling during the LeEix/Eix defense response. These registries have access to over 350000 twin pairs and are a major resource for genetic-epidemiological research. The NSABP C-05 trial compared 5-FU/LV to 5-FU/LV plus alpha-interferon. The rigorous methodology used to develop and test the QIs will result in QIs that are meaningful, valid, feasible to collect and efficiently measurable, amenable to improvement, and selected by experts in the emergency medicine field.

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In 14 premature babies with clinical signs of sepsis the concentrations of serum lysozyme were particularly decreased in cases of septicemia caused by gram-negative organisms. Image reconstruction is demonstrated by using frequency-domain photon migration measurements on 256-cm(3) tissue-mimicking phantoms containing none, one, or two 1-cm(3) heterogeneities with 50- to 100-fold greater concentration of Indocyanine Green dye over background levels. Immunodiagnosis of human dirofilariasis by enzyme-linked immunosorbent assay using recombinant DNA-derived fusion protein. The importance of measuring and recording vital signs correctly. We coupled different reporter gene assays to unique expressed oligonucleotide tags (EXTs) that serve as identifiers and quantitative reporters.

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Correlative light and electron microscopy aims at combining data from different imaging modalities, ideally from the same area of the one sample, in order to achieve a more holistic view of the hierarchical structural organization of cells and tissues. As an increasing number of couples choose to postpone childbearing, they should be informed that paternal age over 40 years is an important risk factor for failure to conceive. Vaccine-adverse event reporting system: an essential tool for monitoring vaccine safety. For unequivocal assignment, the hitherto unknown metabolites 3 and 4 were synthesized and characterized by spectroscopic techniques. This paper examines whether a prehospital NEWS derived from ambulance service clinical observations is associated with the hospital ED disposition.

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The impulse for this increase is very probably the change from high fat milk diet to high carbohydrate standard laboratory diet, the decrease of blood lipids, the activation of thyroid gland and changes of sensitivity of hepatic cells towards thyroid hormones. The effect of array configuration parameters on the sensitivity of the proposed method to random and coherent noise is discussed. Based on observations that mutations of GATA-3 are responsible for the HDR-syndrome (hypoparathyroidism, deafness, renal defects) and that GATA-transcription factors have an important role to play in inner ear development, we hypothesized that these transcription factors may be involved in regulatory changes of prestin transcription. Associations between cigarette smoking, hormone therapy, and folate intake with incident colorectal cancer by TP53 protein expression level in a population-based cohort of older women. Managers of establishments were also asked whether they conducted tobacco product sales promotions within establishments. We show that the slow steps of transcription initiation, including DNA scrunching/RNAP-promoter rotational changes during 5- to 8-nt synthesis, not the major conformational changes, dictate the overall rate of EC formation in T7 RNAP and represent key steps that regulate the synthesis of full-length RNA. Surgery as a teachable moment: lost opportunities to improve public health. Most cases are caused by dominantly inherited mutations or deletions of the PAX6 gene, which encodes a transcription factor that is essential for the development of the eye and the central nervous system. Response Re: Evaluation of renal function after successful treatment for unilateral, non-syndromic Wilms tumor.

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25 health professionals who regularly provided care to people admitted to hospital with concurrent dementia. People with eating disorders form a unique group of mental health consumers to survey for satisfaction. A substantial amount of data suggests that both RNA and DNA tumor viruses are associated with human cancer. Rate constants are classified into two groups: those of the order of unity and those of the order of epsilon (much less than 1) or less, and are represented in the schemes by thick and thin arrows, respectively. The iontophoretic injection of lithium into snail neurones reversibly increased the resting relative potassium permeability (PK). Glabellar rhytids are a common finding in patients with TAO, and tend to be present in patients with diplopia and multiple stigmata of the disease. Operative procedure and indications for surgical management of pulmonary metastasis of choriocarcinoma. Home- and community-based care interventions that attempt to increase informal support networks and provide instrumental help (cooking, cleaning, transport) on short notice during flare-ups could augment existing ( amaryl 0.5 mg but limited) informal caregiving, help severely mentally ill individuals remain independent, and reduce the likelihood that loss of an informal caregiver would result in unwanted outcomes. Tracking central hypovolemia with ecg in humans: cautions for the use of heart period variability in patient monitoring. Pneumocystis carinii pneumonia (PCP) presenting as bilateral upper-lobe cavitary disease is rare.

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In addition, the study evaluated the usefulness of QuantiFERON TB-2G((R)) (QFT-2G). National antidepressant prescribing in children and adolescents with mental health disorders after an FDA boxed warning. Seven horses with RAO were exposed to moldy hay until they developed airway obstruction on 3 separate occasions. Cranio-orbital-temporal neurofibromatosis: are we treating the whole problem?. N2-Sulfomethylguanine, N6-sulfomethyladenine, N4-sulfomthylcytosine and N6-sulfomethyl-9-beta-D-arabinofuranosyladenine were isolated as crystals and characterized. Perovskite-type calcium titanate nanoparticles as novel matrix for designing sensitive electrochemical biosensing. A total of 147 tubes containing 1 x 10(5) MRC5 cells were divided into seven tenormin 50 mg uses equal groups. The macrolide antibiotic roxithromycin is effective against acne associated with inflammation, but the mechanism by which this is achieved has not been clarified. A multilevel spinous process splitting and distracting laminotomy technique with complementary spacer insertion between the laminar parts was developed. Prosthetic rehabilitation of a mandibular gunshot defect with an implant-supported fixed partial denture: a clinical report.

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