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Alendix (Alendronate)
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Alendix

Alendix slows calcium loss from bones. It helps to make normal healthy bone and to slow bone loss in people with Paget's disease and osteoporosis. It may be used in others at risk for bone loss. It is more popular than comparable drugs. It is available in generic and brand versions.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Arava, Vasotec, Benemid, Ventolin, Cytoxan, Daklinza, Neuropill, Cardol, Levovid, Liporest, Celexax,

Also known as: Alendronate

Description

Generic Alendix is a drug which helps to fight with postmenopausal osteoporosis, steroid-induced osteoporosis, Pagets disease of bone. Generic Alendix is a medicine which belongs to the group of medicines called bisphosphonates. Alendix is also known as Alendronic acid, Alendronate sodium, Ostofos. Generic Alendix works by preventing bone breakdown and increasing bone density (thickness). Generic name of Generic Alendix is Alendronate. Brand name of Generic Alendix is Alendix.

Dosage

Take Alendix Plus D exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Alendix Plus D tablets are taken once each week. Choose the day of the week that best fits your schedule. Every week, take one Alendix Plus D tablet on your chosen day.

Take the Alendix Plus D tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.

Take the tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking this medicine.

Do not crush, chew, or suck the tablet. Swallow the pill whole.

After taking an Alendix Plus D tablet, carefully follow these instructions:

Do not lie down or recline for at least 30 minutes after taking Alendix Plus D. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Alendix Plus D. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. You may not need to take Alendix Plus D for longer than 3 to 5 years if you take it for osteoporosis.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Alendix Plus D. You may need to stop using the medicine for a short time.

Alendix Plus D is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

Detailed Alendix Plus D dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drink a full glass of milk and call your local poison control center or emergency room right away. Do not make yourself vomit and do not lie down.

Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid taking any other medicines for at least 30 minutes after taking Alendix. This includes vitamins, calcium, and antacids. Some medicines can make it harder for your body to absorb alendronate.

Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.

Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.

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Antibodies to two primary bile acids, cholylgycine and chenodeoxycholylglycine, and to two secondary bile acids, sulfolithocholylglycine and deoxycholylglycine, were raised in rabbits after the acids were covalently linked to albumin by use of the carbodiimide reaction. The early molecular epidemiology of the swine-origin A/H1N1 human influenza pandemic. While the neurochemical basis of MMN has been linked to N-methyl-D: -aspartic acid (NMDA) receptor function, the roles of the dopaminergic and/or the serotonergic systems are not fully explored in humans. Fluid and solute transport using different sodium concentrations in peritoneal dialysis solutions. 1,3-Diazepanes of natural product-like complexity from cyanamide-induced rearrangement of epoxy-delta-lactams. Experiments were conducted on rats with an experimental hypo- and hyperthyroidism. To determine the physicochemical properties of the mutanase of Trichoderma harzianum isolated from China and to study the influence of mutanase on the adherence of oral Streptococci and the structure of oral biofilms. We conclude that YAP O-GlcNAcylation is a potential therapeutic intervention point for treating liver cancer associated with high blood glucose levels and possibly diabetes. The formation of variants with a reversion of properties of transformed cells.

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Addition of dexamethasone to either diluted or commercial artificial surfactant, Survanta (Abbott Industries, Sydney, NSW, Australia), did not alter the surface properties of the surfactant. A further understanding of the biophysical and biochemical mechanisms involved in these processes would have important ramifications for a range of fields including differentiation, migration, mechanotransduction, DNA repair, and tumorigenesis. Lupus anticoagulant antibodies have never been reported to disappear after either allogeneic or autologous bone marrow transplantation in humans. High-risk patients with stage II colon cancer may benefit from adjuvant chemotherapy, but identifying this patient population can be difficult. Controlled thermolysis of silver alkylcarboxylates with primary alkylamines was investigated as a facile synthetic method of silver nanoparticles. The results of the present study collectively indicated that miR-384 expression level was downregulated in Ang II-treated HUVECs and miR-384 overexpression protected HUVECs against Ang II-induced apoptosis by negatively regulating Herpud1.

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Furthermore, zirconia demonstrated significantly greater in col 1 expression in 48 and 96 hours compared with titanium. A new polydactyly/imperforate-anus/vertebral-anomalies syndrome?. We describe the pattern of dental development of Hominid XVIII from the Middle Pleistocene Sima de los Huesos (SH) site of the Sierra de Atapuerca (Burgos, Spain). Role of intronic E- and N-box motifs in the transcriptional induction of the acetylcholinesterase gene during myogenic differentiation. Instead we suggest that autoinhibition of DNA binding occurs through an indirect steric and/or electrostatic mechanism. Protein expression levels of apoptosis-associated proteins and multiple inflammatory cytokines were determined by Western blot analysis.

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Our findings suggest that ablation lesions produced with an RMN-guided 8-mm catheter are less effective irrespective of CTI anatomy. Intermethod calibration of alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) results: application to Fibrotest and Actitest scores. State of and prospects of the standardization of medical engineering terminology. An easy method for primary culture of chicken hepatocytes was developed to study the influence of dioxin on birds. For each identified nuclei subpopulation, the parameters of population size, fractions of nuclei in each phase of the cell cycle and computation of DNA ratios can be discerned. Isolated bilateral subconjunctival hemorrhages developed in an adult patient after ingestion of a large amount (6.48 g) of aspirin. After repeated injections in a 6-week period, differences in these values could not be demonstrated. Correspondingly, the reverse mutation (guinea pig T254S) resulted in a fast, human-like time constant of desensitization.

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To assess the feasibility of using pegylated liposomal doxorubicin (PLD) as a consolidation therapy in patients with advanced ovarian cancer who have attained a clinically defined complete response to initial platinum/paclitaxel-based chemotherapy. We show that, because of the novel form of band crossing, the new TM cannot be described by the established results that characterize the topology of the Dirac and Weyl nodes. Thus, both the unique NH(2)-terminal domain and the COOH-terminal Hsc70-binding domain of Bag1L are simultaneously required for its function as an AR regulator, whereas the conserved ubiquitin-like domain is expendable. Nuclease S1 from Aspergillus oryzae was used to digest the unpaired ssDNA, resulting in a distinct labeling of the alpha-heterochromatin in the chromocenter and a small amount of diffused labeling in the proximal beta-heterochromatic part of the X-Chromsome. Histologic examination of tissue specimens showed many epithelial tubules within loose connective tissue and a disorganized muscular coat. Our results demonstrated that the increased expression of RhoA in HUVE cells significantly enhanced the morphogenetic changes and cytoskeletal reorganization of the transfected cells, and also enhanced cell migration and angiogenic capacity in vitro, suggesting that RhoA plays an important role in the process of HUVE cell migration and angiogenesis in vitro. Prior stressor exposure sensitizes LPS-induced cytokine production.

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The expression levels of HBx were negatively associated with those of ARID2 in hepatocellular carcinoma tissues. To repair the huge incisional hernia of abdominal wall, a new surgical method was introduced. Changes in ventricular effective refractory periods after two extrastimuli and ventricular electrical instability. Aryliminopropadienethiones 9 have been generated by flash vacuum thermolysis of isoxazolones of the type 5 and characterized by mass spectrometry and matrix isolation IR spectroscopy in conjunction with DFT calculations and chemical trapping. The exact mechanism of the action of arsenic is not known, but several hypotheses have been proposed. Septins, a conserved family of membrane and cytoskeletal interacting GTPases, form intracellular diffusion barriers during cell division and neurite extension and are expressed in myelinating cells. The essential oil was obtained by a steam distillation method and analyzed using GC-MS. The scanning electron microscopy (SEM) showed that the erythrocytes adhered to the parasite surface and were phagocytosed.

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Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive insulin therapy, by The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. When NK cells were treated with varying concentrations of palm vitee (mixture of alpha-tocopherol and tocotrienol), maximum effect was observed at the dose mixture of 12 micrograms and 24 micrograms alpha-tocopherol and tocotrienol, respectively. Open questions are identified and issues for further research are suggested. Consistent with the computational prediction, overexpression of RIN1 in cultured cells decreased the phosphorylation of CRAF and its downstream targets. Nonclinical and clinical data to date indicate that pertuzumab provides a broader HER2 blockade through the inhibition of HER2 heterodimerization. Awareness of this case may prevent pathologists from misdiagnosing similar lesions as NK/T-cell lymphomas. To explore how a multidisciplinary approach, combining modern visualization and image processing techniques with innovative experimental studies, can augment the understanding of tumor development.

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Effect of prolactin on serum proteins of hypophysectomized pigeons. There was a correspondence among HPV genotypes in invasive and associated PeIN. Resting echocardiographic parameters were converted to z-character. Post-transfusion purpura (PTP) is a recently separated category of thrombocytopenic purpura occurring mainly in women. These findings show that central nervous system stem/progenitor cells can survive and differentiate into neurons and peripheral glia after xenotransplantation to the adult dorsal root ganglion. Foxp3 demethylation was associated with tolerance induction, indicating that Treg cells play an important role in the regulation of peanut sensitivity and maintenance of immune homeostasis. Standard cardiac resynchronization therapy with a second right ventricular lead for severe right ventricular heart failure in 2 patients with repaired tetralogy of Fallot. These five residues occur in four short sequences conserved throughout the family, and within such sequences some key amino acid residues are related to enzyme specificity. The insulin-like growth factor II gene (Igf2) is paternally expressed in the fetus and placenta.

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Modeling small-scale dairy farms in central Mexico using multi-criteria programming. This discrepancy seems to be caused by the differences in mechanoreceptor types which take part in subjective responses: suprathreshold sensation depends on several types of mechanoreceptors, whereas vibrotactile thresholds depends mainly on RA receptors (Meissner corpuscles). Use of selenium to alleviate naphthalene induced oxidative stress in Trifolium repens L. In some patients, aortitis is identified either pathologically or radiologically in the absence of clinical evidence of a systemic vasculitis. Orthotopic replacement of the urethra using the Mitrofanoff principle is suitable in highly select female patients who need continent diversion or a catheterizable conduit but who will not accept an abdominal stoma. Management of left ventricular thrombosis in patients with apical aneurysm. A difference in the distribution of RBMY1 copy number was observed between the group with normal sperm motility and the group with asthenozoospermia. Cytochrome P-450 induction during yeast organism growth on various substrates.

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A novel cytotoxic cerium complex: aquatrichloridobis(1,10-phenanthroline)cerium(III) (KP776). Results of arthroscopic Bankart repair with Hill-Sachs remplissage for anterior shoulder instability. Such patients should be ideal candidates for intermittent colchicine therapy. Based on these data, several Akt inhibitors are about to enter phase 3 trials. Dual inhibition of ER and IGF1R enhanced growth inhibition in the four HER2 positive cell lines tested and caused an increase in cell cycle arrest in G1 in BT474 cells. Smoking is known to be a risk factor for AMD and this study suggests that smokers are at no more risk of developing neovascular than atrophic lesions. We evaluated the association of single nucleotide polymorphisms (SNPs) in VEGF genes and their receptors (VEGFR) with the adalat cc tablets response rate to ranibizumab in 366 patients with neovascular AMD. Unusual layer-thinning transition observed near the smectic-A-isotropic transition in free-standing liquid-crystal films. The Minos-derived vectors insert in different locations in the mammalian genome. Maternal mortality among migrants in Western Europe: a meta-analysis.

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Shear stress, temperature, and inoculation concentration influence the adhesion of water-stressed Helicobacter pylori to stainless steel 304 and polypropylene. The HFC of the mammary gland is increased 2-3 times during lactation as compared with the fully developed gland in pregnancy. During the past decade, experts have devoted substantial efforts to quality improvement for managed care. SWR/J female mice, 8 hr water deprived, were injected intraperitoneally with 0, 10, 50, 200, and 800 mU of aqueous pitressin, 5 min prior to presentation of water. Skin cancer risk in relation to toenail arsenic concentrations in a US population-based case-control study. Small-scale co-management for the sustainable use of Xilingol biosphere reserve, inner Mongolia.

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