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Alfresh (Alprazolam)
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Alfresh

Alfresh is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alfresh, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alfresh is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alflux, Alfresh, Alpanol, Alparazole, Alpkair, Alpranex, Alprasert, Alprine, Alprose, Alprowon, Alzex, Alzin, Alzom, Anxigo, Anxyl, Anzocalm, Aryalam, Balzam, Betapax, Cardilax, Copax, Cqlam, Diprex, Flumusa, Himzolam, Isorest, Mentolift, Propnix, Restyl, Samitol, Selam, Somaspas, Somnarest, Tenil, Tenschem, Xylonite, Zolipax, Zolran, Zopral

Similar Products:
Remeron, Zofran, Elocon, Depakote, Estrace, Levothroid, Benicar, Tetralisal, Levofloxacina, Alcicalm, Permiriv, Tramakind,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alfresh dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alfresh XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alfresh dosage information

Side effects

The most common side effects associated with Alfresh are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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IGF-I stimulation of extracellular acidification is not linked to cell proliferation for autocrine cells. A single oral dose of RWJ-67657 prevented neutrophil and endothelial activation after endotoxin infusion. Evidence for carrier-mediated transport of monosaccharides in the Ehrlich ascites tumor cells was provided through kinetic analysis of data obtained by: (a) studying sugar uptake by dilute cell suspensions with an optical densimetric apparatus, (b) studying sugar uptake by thicker cell suspensions by means of direct chemical analytical methods using packed cell plugs, (c) observing the effects of a competitive inhibitor upon sugar uptake with the chemical analytical method, and (d) measurement of tracer uptake of a high affinity sugar in thick cell suspensions in the absence of net movement. The objective of this study was to examine the differential gene expression in the liver of P. The survey data also showed that open defecation and drinking unboiled water were common behaviours, enhanced by a lack of knowledge regarding the transmission of the parasite, perceived financial barriers to the implementation of control measures, lack of public sensitization, as well as a lack of self-efficacy towards control of the parasite. Our results demonstrate that bacterial N-OST can be tailored to specific polysaccharide substrates by structure-guided protein engineering. The frequencies of Ag-specific IFN-gamma and interleukin (IL)-4-secreting cells were determined using an enzyme-linked immunospot assay, which demonstrated that the frequency of IFN-gamma-secreting cells was significantly higher in mice immunized with p53 and Flt3L than in mice receiving Flt3L, excipient, or p53 treatment alone. The prognosis of patients with metastatic GAC remains poor, with a median overall survival of less than 1 year in patients treated with currently available therapies.

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Although vitamin B12 deficiency is not a primary target of newborn screening (NBS) programs, measurements of propionylcarnitine (C3) and its ratios with acetylcarnitine (C3/C2) and palmitoylcarnitine (C3/C16) may incidentally identify vitamin B12-deficient newborns. A total of 193 preterm infants with RDS and 186 preterm infants without respiratory problems were included in this study. The amount of transcript increased with 5-azacytidine treatment of C3H10T1/2 cells and the transcript was highly expressed in mouse testis. Using the polymerase chain reaction and primer pairs specific for the respective constant region and VH or VL family, rearranged variable region gene segments were amplified from cDNA from individual cell lines. Hysteresis and stress adaptation in the human respiratory system. A Sequential Approach to the Treatment of Severe Papulopustular Rosacea Not Responding to Traditional Treatment. Thus, some males were displaying to females for several months before the breeding season began. We report a case of a 6-year-old girl of Afro-Caribbean origin, known to have sickle cell disease (SCD), with recurrent history of jaundice and abdominal pain. We conducted a community-based survey in a large rural, mountainous area across four districts of the Nord department including areas with good versus poor accessibility by road, and rapid versus delayed response to the outbreak to document the true cholera burden and assess geographic distribution and risk factors for cholera mortality. In human melanoma cell lines with different metastasis potential (WM35, WM1341b, WM983a and WM451), expression of KAI1 showed moderate expression (integral light density values are 0.1798, 0.1582, 0.1501, 0.1800 respectively).

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Ultrasound detection of aortoenteric fistula in a patient with sepsis. We find that the preferred system gamma can be predicted in all conditions and for all images by a simple model that searches for the value that best flattens the lightness distribution, where lightness is modeled as a power law of onscreen luminance. Sequential barcoded fluorescent in situ hybridization (seqFISH) allows large numbers of molecular species to be accurately detected in single cells, but multiplexing is limited by the density of barcoded objects. Cardiac echinococcosis is a very rare disease, especially in girls. The need is articulated for empirical research that focuses on reform as an implementation process, to provide further insight in what we know about its impact on educational outcomes. We observed hypocoagulation caused by the reduced activity of the prothrombin complex factors, disaggregate thrombocytopathy, and endotheliosis with fibrinolysis inhibition in subcompensated chronic colostasis with continuous reduction of colon bacillus levels and pathogenic microflora appearance. Altogether, our results suggest that the amino-terminal part of KGF and bFGF plays an important role in determining their receptor binding specificity. This is the first report of chronic inflammatory multiorgan hepatobiliary pancreatitis, along with fibrosis and calculi formation induced reliably utilizing oral DBTC administration in TNFR1/R2 deficient mice. Radicular pain is known to be associated with DRG injury caused by intervertebral disc herniation. The mean EQV stresses were 64.145 MPa, 77.925 MPa, and 78.500 MPa, respectively.

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Second, interpretative phenomenological analysis of 25 interviews with people purposively selected from among the survey sample identified general strategies and specific tactics used by young people to manage opportunities to drink. The 16 priority PAHs were determined in the water dissolved phase (DP), suspended particulate matter (SPM) and sediments collected from 21 sites in four different seasons. Our findings add to the available information regarding the problems encountered when ascending to high altitude with children and support the importance of close monitoring of young children during ascent to high altitude. A factor analysis of the meanings of anorexia nervosa: intrapsychic, relational, and avoidant dimensions and their clinical correlates. Our study is the first report of ACE I/D and MTHFR C677T polymorphisms in fibromyalgia syndrome. The results showed that left anterior putamen coactivated with clusters predominantly in left hemisphere, encompassing regions directly associated with language processing, a left posterior putamen network spanning both hemispheres, and cerebellum. Combined lung-liver transplant can be considered for patients with advanced pulmonary disease. Impact on sexually transmitted disease spread of increased condom use by young females, 1987-1992.

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Ultrastructure of methylcholanthrene-induced fibrosarcomas in the Swiss albino mouse. A sample of 320 street-involved people who use drugs participated in a structured, interviewer-assisted survey in Edmonton, Canada. Transport simulation was performed for a reclamation scenario in which the source of acidic seepage will be terminated after 5 years and the plume will then be flushed by uncontaminated upgradient groundwater. We present a Bayesian probabilistic framework for quantifying and propagating the uncertainties in the parameters of force fields employed in molecular dynamics (MD) simulations. The bcsD gene can improve the crystalline structure of the bacterial cellulose but there is not any significant difference between the amounts of cellulose produced by the recombinant and wild type E.

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Factors controlling the interconversion of enzyme-substrate compounds of pig heart lactate dehydrogenase. Whenever the probabilities are only slightly distorted, the information loss is shown to be quadratic in the distortion. Here, we report that somite hematopoiesis, a previously unwitnessed hematopoiesis, can generate definitive HSCs (dHSCs) in zebrafish. To evaluate the efficacy of Counselling and Advisory Care for Health (COACH) programme in managing dyslipidaemia among primary care practices in Malaysia. This meta-analysis provides evidence that short sleep duration in children is associated with a significantly increased risk of obesity. Effect of different mixing and placement methods on the compressive strength of calcium-enriched mixture. No significant differences were found between the two groups in their evaluation of nasal pain (2.8 cm lidocaine group vs. Raman analyses show changes in the spectral features associated with various biochemical compounds, which are interpreted as the result of detrimental freeze drying effects on the bacterial cells. Serum small-dense LDL abnormalities in chronic renal disease patients. We note that different measures capture different aspects of benefit, and some may be more reliable than others or more representative of clinically relevant benefit.

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Loss of Sema3-Nrp1 signaling resulted in acute respiratory distress and high neonatal mortality. Prehospital electrocardiographic computer identification of ST-segment elevation myocardial infarction. Primary research articles were identified by MEDLINE search (1966-May 2001) and through secondary sources. Stroke is a major public health concern with few positive phase III clinical trials and a shortage of stroke care expertise. This led to a significant decrease in prosthesis misfit for the test implants compared with the control implants. Therapeutic options are heavily curtailed by a dearth of knowledge about the condition, with low numbers of participants and poor trial recruitment impeding research. The triggering of apoptosis was probably related to failure of spindle formation at cell division, supporting the contention that TCBZ inhibits microtubule formation. We describe the case of a rare cause of severe coronary artery disease in a young woman without cardiovascular risk factors. Hospitalized patients have been shown to make several errors in using metered-dose inhalers (MDIs), which can lead to poor medication delivery. During the forty-year life of the Journal of Ambulatory Care Management, revolutionary transformations have occurred in the roles of existing health professions, as has the emergence of new categories of health professionals.

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A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. According to the international consensus for ANCA testing, presence of ANCA should at least be screened for by IIF and, if positive, followed by antigen-specific immunoassays. Sirolimus and tacrolimus were given separately and together to female non-obese diabetic (NOD) mice from age 12 to 35 weeks. Clinicopathologic factors associated with OS were identified using Cox proportional-hazard modeling, adjusting for factors associated with receipt of AC. Gradient centrifugation in colloidal silica-polysaccharide media. While these so-called directed assembly techniques have proven viable, much of this effort has focused on the assembly of periodic arrays of spherical or near-spherical nanostructures comprised of a single element. Neuraminidase inhibitors might be useful in preventing genesis of autoimmunity during infection, although this possibility has not been formally tested. All patients had a successful ES, conventional in 34, precut-knife in 3, and with the rendezvous technique in 4 patients.

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