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Alpaz (Alprazolam)

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Alpaz is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpaz, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpaz is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Aldip, Alparazole, Alpaz, Alprasert, Alsert, Altok, Altrex, Alzac, Alzotime, Ambutech, Aryalam, Axizox, Benzolam, Calmtec, Censir, Cozac, Dazolam, Dexolam, Elflu, Emlol, Fluxin, Kurelam, Luzarn, Norex, Normatine, Paxor, Prazolam, Pronil, Prosanti, Rescalm, Restam, Sinzolam, Sozox, Tenzorid, Tranisol, Trapose, Zolax

Similar Products:
Danocrine, Singulair, Asacol, Elocon, Silagra, Dramamine, Dilantin, Celexa, Adalat, Cluvax, Sanpred, Rodixina, Colchicine, Cardizem, Cettop, Apodruff, Bisoblock, Ocepred,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpaz XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpaz for medical reasons, the best way to avoid a Alpaz overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpaz consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpaz XR dosage information

Side effects

The most common side effects associated with Alpaz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alpaz if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alpaz is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alpaz while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alpaz is not approved for use by anyone younger than 18 years old.

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Do the emotional content and meaning of sentences affect the kinematics of successive motor sequences?. Researchers from 5 Japanese universities have developed a plant growth facility (Space Plant Box) for seed to seed experiments under microgravity. The resolution of pouchitis with metronidazole points to an anaerobic aetiology. This review is dedicated to David Walker (1928-2012), a pioneer in the field of photosynthesis and chlorophyll fluorescence. Electron spin resonance study of irradiated bone and its constituents. Simultaneous biventricular stimulation for ventricular arrhythmias. By presenting 4 cases we want to point out the diagnostic possibilities and the operative management of such rare injuries. GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia.

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Perception of midline diastema differs among individuals and cultures. Patients with type 2 diabetes were subdivided on the basis of their plasma insulin response to oral glucose into hyperinsulinemic (H-DM) and normoinsulinemic (N-DM) groups of 15 patients each. The purpose of this article was to explain how rheology, the study of the flow of matter, can be used to help physicians differentiate between dermal fillers targeted to certain areas of the face. A prospective, double-blind, randomized, placebo-controlled trial of a continuous infusion of ketorolac tromethamine in 1 L of normal saline vs placebo was performed in 135 patients aged 18 to 75 years after laparoscopic donor nephrectomy or percutaneous nephrolithotomy completed from October 7, 2008, through July 21, 2010. Standard of care for chronic hepatitis C (CHC) in India is peginterferon and ribavirin (RBV). Specific objectives consist of comparing and contrasting ethno-racial variations in 1) definitions of recovery, 2) barriers to recovery, and 3) facilitators of recovery. In this study, we cloned and compared nucleotide sequences for three low-copy DNA fragments from the B and D genomes of several wheat accessions and from diploid relatives of the B and D genomes. In the first year of the pilot project in the Leningrad Region, the DOTS strategy revealed feasibility and moderate efficacy among new pulmonary tuberculosis cases who were either smear-positive or showed extensive lung lesions on chest X-ray, and who were therefore of high epidemiological and medical priority. There was extensive histolysis in the retinal epithelium and underlying nervous and connective tissues.

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The objective of this project was to study the expression of MMP1 in surgical and radiation-impaired wound healing and its effects on the healing process and tissue remodeling. METHODS The authors reviewed a retrospective cohort of patients with iatrogenic injuries to the intracranial vasculature that were treated with the PED between 2012 and 2016. In this station, frequent biomass decompositions and anoxic crises created critical conditions for life favouring organisms with reduced life cycles, younger individuals and the epifaunal species instead of the infaunal ones. The genetic abnormalities underlying AML affect signal transduction pathways, transcription factors and epigenetic modifiers. Model predictions point to parameters involved in the transport of Mig1 in and out of the nucleus as a majorsource of cell to cell variability. Cell-free supernatants were harvested from fibroblast cultures and later subject pre-osteoblasts to investigate there capacity to modulate cell viability and differentiation mechanisms, reporting the possible involvement of Shh signaling as a paracrine mechanism. We present an expanded prospective model of surveillance, cancer rehabilitation assessment, and referral efforts using a multidisciplinary team approach. The association of KPC2 with KPC1 was found to stabilize KPC1 in a manner dependent on the STI1 domain of KPC2.

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Monoclonal antibodies are commercially important, high value biotherapeutic drugs used in the treatment of a variety of diseases. Can animal habitat use patterns influence their vulnerability to extreme climate events?. This is the first report to differentiate the larger class of these conserved proteins from SulA proteins and characterizes MadR1 effects on the mycobacterial cell. A first case report of empyema caused by Tetratrichomonas species in Japan. In addition, the established identification algorithm is very economical and improves time-to-result. Sensitization by metabolic inhibitors of isolated rat intestine to the effects of sympathomimetics. Moreover, confocal microscopy analysis revealed that budded virions can enter the cytoplasm but are unable to enter the cell nucleus. In response to the rising demand by patients and their families for complementary health approaches, hospitals are increasingly integrating complementary health approaches with their conventional medical practices to create healing environments. Augmentation of existing clinical and imaging data by 3D prototypes allowed successful execution of complex surgeries for all five patients, in accordance with the preoperative planning. Arguments against biliary drainage before pancreatoduodenectomy have been gaining momentum recently.

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Daily subcutaneous administration of GHRH-A is feasible and safe in a large animal model of subacute ischemic cardiomyopathy. Effect of endocrine system on the permeability of the hematolabyrinthine barrier. In order to quantitatively analyze the stability of the equilibrium points, we focused on the basic reproduction numbers. A sample of capillary BG, fasting, once per week correlates better with the HbA1c than a fasting PG every 2-3 months. We conducted a spatial grid-based analysis using projections of future climate generated by the National Center for Atmospheric Research Community Climate System Model version 4 for two representative concentration pathway scenarios (RCP2.6 and RCP8.5), adopted by the fifth phase of the Coupled Model Intercomparison Project to study the areas suitable for the cultivation of rice and maize in China.

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Disease is thought to result from the sequestration of parasites in the small blood vessels of the brain and the deregulation of key immune system elements. The underlying database structure is presented, the import process for extracting incoming reports is described and the export process for generating new outgoing standardized reports is briefly illustrated. Transient acute inflammatory reaction, infections, and skin diseases localized on tattooed area were excluded from this study. However, even though beta-arrestin1 binds directly to the carboxyl-terminal tail of mGluR1a and redistributes with mGluR1a to endosomes, neither beta-arrestin1 nor beta-arrestin2 seems to contribute to mGluR1a desensitization in HEK 293 cells. The matricellular protein SPARC (also known as osteonectin and BM-40) is expressed abundantly in lens epithelium. These results provide biological plausibility for a clinical trial to repurpose colchicine as a RV-directed therapy for PAH. This trial provides first evidence of clinical efficacy of vidofludimus in IBD.

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Recurrent pulmonary thromboembolism in a patient with systemic lupus erythematosus and HIV-1 infection associated with the presence of antibodies to prothrombin: a case report. Furthermore, neuronal activity was necessary for the up-regulation of glutamate release and synapsin I, synaptotagmin, and synaptophysin expression, but not of GABA or GAD65/67. For these patients, FGFR4 may be a potential therapeutic target. An elevated amniotic fluid matrix metalloproteinase-8 level at the time of mid-trimester genetic amniocentesis is a risk factor for spontaneous preterm delivery. These studies have led us to propose a mechanism for the reaction that proceeds through an initial N-chlorination of the chiral catalyst-substrate complex, followed by a 1,3-sigmatropic shift of the chlorine atom to the enamine carbon atom. The kinetics of oxygen geminate binding with the taxonomic substates of MbO2 are reported. In the present review the intrinsic anafranil 10 mg kaufen pharmacodynamics of each drug, together with the synergism produced by the amoxicillin/clavulanic acid association, are also reviewed and analysed.

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Role of physical activity for the prevention and rehabilitation of osteoporosis. Botulism is characterized by flaccid paralysis, which can be caused by intoxication with any of the seven known serotypes of botulinum neurotoxin (BoNT), all of which disrupt synaptic transmission by endoproteolytic cleavage of SNARE proteins. Working Alliance, Interpersonal Problems, and Depressive Symptoms in Tele-Interpersonal Psychotherapy for HIV-infected Rural Persons: Evidence for Indirect Effects. The clinical use of cisapride in gastro-oesophageal reflux disease, with particular focus on the long-term treatment aspects. THE PHOTOACTIVATED CERCOSPORA TOXIN CERCOSPORIN: Contributions to Plant Disease and Fundamental Biology. Insertion of eukaryotic promoters upstream adipex 30 mg permits the efficient expression of LacZ in bacteria cells. Incidence of chromosomal aberrations and micronuclei in cave tour guides.

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Hydrogen peroxide induced intensive oxidative stress accompanied by suppression of protein-synthesizing function. Vasculitis neuropathy mimicking lower limb mono-radiculopathy: a study and follow-up of 8 cases. Linear magnetoresistance caused by mobility fluctuations in n-doped Cd(3)As(2). The modular software application manages the many aspects of cell culture laboratory record keeping like detailed information on tissue donor, primary cell isolation/cell line origin, immunohistochemical/molecular biological characterisation, cell countings at passaging/subcultivation/cell aliquotation and cryopreservation. In contrast, the JTCs and LTCs have, as a rule, no invasive and phagocytic activities, while preserving proliferative properties up to 15 day of gestation. Axial loads would be able to generate more uniform stress at the root presenting a greater concentration of load application in the point and the occlusal surface. Oxygen-derived free radicals in kidney in experimental hemorrhagic shock treated by PAF-receptor antagonist BN 52021. All three patients were treated with dapsone 100 mg/day with regression of the clinical manifestations. One subset of 32 annotated genes or open reading frames was identified, and each of these were cloned into the eukaryotic vector pcDNA3.1. The indirect effects of changing climate in modulating trophic interactions can be as important as the direct effects of climate stressors on consumers.

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White Light Emission from Planar Remote Phosphor Based on NHC Cycloplatinated Complexes. ANS evaluation including tilt testing should be considered as preliminary screening in patients with syncope in the absence of definite heart abnormalities. The three patients each had a complete preoperative neurologic deficit. Role of p16(INK4a) cytology testing as an adjunct to enhance the diagnostic specificity and accuracy in human papillomavirus-positive women within an organized cervical cancer screening program. The use of a scatterplot instead of simple classification tables is suggested. All mouse immunoglobulin G (IgG) subclasses except IgG3 were found in serum at comparable levels, suggesting that the immunization induced mixed Th1 and Th2 responses. This behavior is attributed to the combination of the amphipathic nature of the hydrophilic pentaethylene glycol side chain and dendritic effect. Speciation of mercury, tin, and lead compounds by gas chromatography with microwave-induced plasma and atomic-emission detection ( pepcid complete 100 tablets GC-MIP-AED). A doubled thread is passed through 1 edge of the radial tear by the Meniscal Viper and is kept in place without tying the knot.

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The structure of the yeast ArgRS.tRNA(Arg) complex suggested that two residues in the unique N-terminal domain, Tyr(77) and Asn(79), which are phylogenetically invariant in the ArgRSs from all organisms with A20 in tRNA(Arg)s, are involved in A20 recognition. NP tests (Trail Making Test parts A and B, and Symbol-Digit Modalities) obtained within 2 years of CT screened for psychomotor speed and executive function. A high sAng-1/sAng-2 ratio was associated with a longer progression-free survival and a longer overall survival in cervical cancer patients. Primary endpoint was change in NAFLD scores after LAGB and secondary endpoint change in MS criteria. We previously sought to better understand critical components required for HGF-induced epithelial scattering by performing a forward chemical genetics screen, which resulted in the identification of compounds with no previously reported biological activity that we report here. We tested whether job satisfaction mediates the relationship between regulatory fit and mental health. We found strong nuclear immunoreactivity for hMSH2 that was elevated in malignant melanoma and melanoma metastases as compared to acquired nevi. In an analysis of vascular audit data on upper limb vascular trauma over a 10 year period in a major UK injury centre it was found that 15 patients required operation for subclavian or axillary artery injuries. We conclude from these data that, using the enzyme immunoassay against 5beta-androstane-3alpha-ol-11,17-dione-17-CMO, we were able to detect transport/novel environment stress but not the potential disturbance that cows experience during diagnostic procedures. In this study, we conducted a proteome-wide investigation of rhythmic protein accumulation in D.

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Arguably, migraine patients and, more certainly, MOH patients should be screened with HADS in pursuit of best outcomes. In the lead article, Wylie, McAllister, Davidson, and Marshall (2013) note that, even in the relatively affluent Minority World, including Australia, equity in service provision for people with communication disability has not been achieved. In the present study, the preventive effect of single dose of alpha-hederin, its active constituent, has been evaluated on lung inflammation and some inflammatory mediators in lungs of ovalbumin sensitized rat in order to elicit its mechanism. The effect of ADMA on nitric oxide (NO) production was determined by measuring the stable end product of NO, nitrite, in the culture medium using commercial NO kit. Further randomized studies are needed to better define intraoperative transfusion criteria.

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Here we describe the development of a human three-dimensional endocervical epithelial cell model generated by rotating wall vessel bioreactor technology. For example, in primary visual cortex, complex cells code for orientation of a contour but ignore its position to a certain degree. Intracellular intact PTH was higher in U-HP and U-HP-LP rats compared to N-HP animals with no differences between the two uremic groups. This technique can now be routinely applied and provides a convenient tool for the characterization and the identification of B. Observed resistance rates were twice as high as those reported among pregnant women from the same geographic area 2 years prior. In this task, two targets are presented in quick succession and the subject is required to make a saccade to each location as accurately as possible.

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