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Alpose (Alprazolam)

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Alpose is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpose, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpose is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcalm, Alflux, Alfresh, Alpramax, Alprocalm, Altrex, Alzoft, Anxofit, Anzal, Azoslip, Calmef, Coolam, Dazolam, Depoxit, Dipra, Faxtin, Finezol, Luzarn, Onapract, Poize, Pyrex, Rescalm, Samprex, Sertamax, Silam, Somnia, Tenil, Tenrid, Tenscure, Zeftra, Zoloid, Zolran, Zopain, Zotam, Zotin

Similar Products:
Leukeran, Cleocin, Parlodel, Zyloprim, Cordarone, Klonopin, Myambutol, Benicar, Metco, Cytolog, Lorpar, Derisone, Roksimin, Atenodip, Piodart, Omida, Omidip, Zolmic,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpose XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpose XR dosage information

Side effects

The most common side effects associated with Alpose are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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The quantitative risk assessment included the following steps: (i) release of antimicrobial-resistant organisms from the farm, (ii) exposure of humans via consumption of contaminated beef products, and (iii) consequence of the antimicrobial-resistant infection. In this study, we describe the generation and characterization of immortalized macrophage-like cell lines from C/EBPbeta-deficient and wild-type mice. Two participant cohorts were identified: those vaccinated within the last year and those vaccinated earlier. An imbalance in the receptor complexes for IL-19 and IL-20 might contribute to their suspected pathogenic effects. In a crossover study, dogs were randomly assigned (in groups of 10) to receive a single oral dose (20 mg/kg) of doxycycline hyclate without excipients (control) or extended-release formulations (ERFs) containing doxycycline, acrylic acid polymer, and polymethacrylate in the following proportions: 1:0.5:0.0075 (ERF1) or 1:1:0.015 (ERF2). Relation between the blood-pressure effect of angiotensin II and the mean arterial pressure, serum sodium, serum potassium, serum angiotensinase and plasma renin in man. Interstitial cells of Cajal (ICCs) are pacemaker cells that create and coordinate peristaltic motility. The purpose of the study was to examine the impact of teleconsultation designed to improve behavior support to students living in rural communities. Special attention has been paid to the ligand binding to melanocortin 4 receptors and to the development of a fluorescence anisotropy-based assay system using receptors in budded baculovirus particles. A wealth of research has shown that retrieval practice plays a significant role in improving memory retention.

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Conformational changes in pediocin AcH upon vesicle binding and approximation of the membrane-bound structure in detergent micelles. In contrast, serum sL-selectin levels were significantly lower in MM patients compared to healthy controls and tended to decrease as the disease stage progressed. A comparison of two neutralization methods for typing enteroviruses. Effects of shenmai injection on expression of TNF-alpha mRNA in peritoneal macrophages of scald mice. An acclimation period improves CVs of VO(2) and VCO(2.) The similarities in CVs led us to adopt a 3-minute acclimation period for measuring REE. Registration of this trial has been completed with the Australian and New Zealand Clinical Trials Registry: ACTRN12615000817549. To determine whether cofilin, an actin severing protein, is required in this process, the levels of phospho-cofilin (serine-3) were evaluated in cells exposed to FSS. Class I histone deacetylases (HDACs) are often overexpressed in cancer, and their inhibition typically leads cancer cells, but not normal cells, to apoptosis.

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The recent finding that genes for the IL-3 and GM-CSF receptor alpha chain subunits colocalise to a small region of the pseudoautosomal region and the observation that the LIF receptor locus is present in a cluster of receptor genes on chromosome 5 suggest the possibility that subsets of cytokine receptor genes may be organised into clusters. The clinical and radiographic evaluation was carried out at a follow-up periods of 3, 6, and 9 months and statistical analysis was carried out by SPSS version 15.0 statistical analysis software (Chi-square test and fisher exact test). HK inhibited cathepsin G-induced platelet aggregation in a concentration-dependent manner with an IC(50) of 0.48 microM. Their presence in water used for human consumption causes serious health problems, liver beeing the target organ. Sildenafil treatment also improved uterine blood flow, decreased uterine vascular resistance, and improved fetal weights in comparison with untreated sFlt1-expressing mice. Uranium is not metal determined to be carcinogenic (the International Agency of Research on Cancer).

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Primary structure and proteins of measles virus variants passaged in tissue culture were studied. The performance of the proposed method (MC-TGV-SENSE) is assessed on two healthy volunteers at several acceleration factors. PcaR, a transcriptional activator of several genes of the beta-ketoadipate pathway, is required for expression of both pcaF and pcaK, and the pathway intermediate beta-ketoadipate induces both genes. The decision to discontinue its use after only one year did not allow space of time for evaluation of its appropriateness as an assessment tool. The present work evaluates the effect of lidocaine -17 microM- on the hypoxia-induced release of tritiated D-aspartate from rat striatal slices in superfusion. Genomic anatomy permits medicine to become more predictive and preventive.

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Virilizing tumors of the adrenal gland in childhood: report of eight cases. Progress curves analysis as an alternative for exploration of activation-inhibition phenomena in cholinesterases. Most importantly, the absence of a discernible amelioration with dialysis implies that purely structural and not functional alterations lie behind the increased arterial stiffness. The ANRBC counts and hematocrit were significantly higher in infants who were born after PROM than in controls. Purpose of the study was to determine the incidence of aberrant phenotypes in North East Indian patients with acute leukemia.

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To analyze the association between neurological function and MRI-based assessment of the extent of spinal metastases using two different grading systems. tuberculosis genome for promoter regions containing the consensus IdeR/DxR binding sequence. Each layer of the flaps were secured with two key mattress suture for flap coaptation. This review discusses recent progress that has been made in understanding how Arabidopsis integrates environmental and internal signals to ensure a sharp transition to flowering and new insights on the role of the circadian clock in controlling the expression of genes that promote flowering in response to day length. Dissection of the PSR1-induced lipid profiles corroborates its role in coordinating multiple lipid-inducing stress responses. Although we cannot conclude the underlying pathological process of SCF, we believe that these findings may be pivotal for further studies searching the specific roles of CD40/CD40L signaling on SCF phenomenon in coronary vasculature. Ultrasound was useful for evaluating and monitoring multiple organ failure. Two of the eight HRQOL SF-12 scores, role physical and general health, and the physical component summary scores, increased significantly during the intervention period. The use of quality benchmarking in assessing web resources for the dermatology virtual branch library of the National electronic Library for Health (NeLH). This study analyzes the social and geographic distribution of ecological hazards across 368 communities in the Commonwealth of Massachusetts.

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It is known that mobile phones may play a role in microorganism transmission. We separately present analysis of data from retrospective files and prospectively recruited patients presenting with TT (35 retrospective and 42 prospective), NSTEMI (48 retrospective and 75 prospective) and STEMI (20 retrospective and 39 prospective). The protocol described in this case report showed excellent results and achieved all the treatment objectives. This review summarizes the diagnosis and management of each of the listed syndromes in the context of currently available genetic testing. Mortality rates were calculated for 1- to 19-year-olds living in Inuit Nunangat and those living elsewhere in Canada. The disease process, treatment options, physiological and psychosocial implications are presented. Recently, new diagnostic tools such as capsule endoscopy and balloon-assisted endoscopy have been developed, and they are useful in diagnosing gastrointestinal bleeding (OGIB) which can not be detected by traditional enteroscopy.

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This is the first haplosplanchnid cercaria to be described from a Cerithidea species. Propolis application in four-week duration does not have effect on TBARS, SOD, CAT and GSH-Px levels of hippocampus of diabetic rats. Using a specific monoclonal antibody, we demonstrated that the 3a protein displayed a punctate cytoplasmic localization in Drosophila as in SARS-CoV-infected cells. The NRT was piloted with 120 third graders, and showed moderate to strong correlations with other measures of PWM, such as digit span and English non-word repetition. The expression of blaCTX-M in the transconjugants was analyzed using fluorescence microscopy, flow cytometry and qRT-PCR. Laminin, fibronectin and type IV collagen did not consistently modify pericyte adhesion. Applying low-molecular weight supramolecular gelators in an environmental setting - self-assembled gels as smart materials for pollutant removal.

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The properties of free and membrane bound polysomes studied in a cell free system of Bombix mori silkglands. Analogs of generic preparations for the treatment of epilepsy: is their use safe?. This review is an update of the original review published in October 1998. Pharmacologic action of cathecolamines on the central motor neural subsystems is advanced. The C-terminal end of PMT paxil medication drug class was predicted to be a mixed alpha/beta domain, a structure commonly found in catalytic domains. The findings show a right hemispheric dominance within the occipito-temporal and the left middle/medial frontal area for both reading Chinese characters and naming pictures. Inhibition of JMJD6 expression reduces the proliferation, migration and invasion of neuroglioma stem cells. After the delivery, it was found that she had been diagnosed as myotonic dystrophy by the other physician and the neonate was a floppy infant indicating hereditary neuromuscular diseases.

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Random-effects meta-analyses of proportions were performed to determine S. The pharmacokinetics of meropenem in infants and children: a population analysis. The proposed pH buffering and phosphagenic functions of polyphosphate were investigated by subjecting chemostat-cultivated Saccharomyces cerevisiae to alkalinization (NaOH addition) and anaerobiosis. Whole genome sequencing projects, together with more targeted studies, have identified hundreds of DNA-binding proteins that contribute to the patterns of gene expression observed during infection as well as providing important insights into the nature of the gene products whose expression is being viramune dose controlled by these proteins. Radiofrequency current caused slowing of non-reentrant idiopathic right ventricular tachycardia originating from a wide arrhythmogenic area. Participants were asked about their receipt of genetic counseling recommendation or referral. Photocatalytic degradation of leather dye over ZnO catalyst supported on alumina and glass surfaces. A rare injury occurring during laryngoscopy and endotracheal intubation that resulted in perforation of the tongue by an endotracheal tube and the subsequent management of this unusual complication are discussed. The changes in craniofacial growth and development of dental occlusion were studied in children with juvenile chronic arthritis (JCA), and treatment with functional orthodontic appliances (activators) was tested in both JCA and healthy children with distal occlusion.

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Secondary rectal carcinoma occurs by invasion of the rectum by local primaries or by metastatic spread from a distant primary. We also calculated the power requirements during take-off flights in four other species in the family Phasianidae tramadol 50 mg indication . Two such genes encoding the LMP2 and LMP7 proteasome subunits are located in this high-risk MHC genomic region. However, analysis of the effects of psychostimulants after either destruction of noradrenergic neurons or pharmacological blockade of alpha1-adrenergic receptors led to conflicting results. The rapid and sensitive detection of nitroaromatic compounds is of great significance for human health, the environment, and public security. There are pathophysiologic similarities between calcification and atherosclerosis because both are the product of an active inflammatory process. Findings from observational studies suggest that sex hormone-binding globulin (SHBG) and endogenous sex hormones may be mediators of the putative relation between coffee consumption and lower risk of type 2 diabetes.

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Importantly, this tenormin dosage range analysis yields experimentally testable predictions on the role of Myc, which could have therapeutic implications. However, a minimum cognitive capacity or training ability seems necessary for the training to be beneficial, with some individuals showing little improvement in performance. Each wavelet at the lenslet aperture was converged into a voxel in the substrate, with its coordinates encoding the angle of incidence and curvature of the wavelet. The mental health of sexually trafficked female survivors in Nepal. The four mitotic cystocyte divisions were frequently inhibited by stwl mutations.

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Abalone, Haliotis discus hannai Ino, can synthesize myo-inositol de novo to meet physiological needs. Several essential factors involved in the vesicle transport have been isolated so far. The presence of FcgammaRIII on human macrophages makes it possible that the IgG, FcgammaRIII, macrophage, and PAF pathway also contributes to human anaphylaxis. Influence of polymyxin B and normal rabbit serum on erythrocyte modifying capacity of common enterobacterial antigen. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Over the years, efforts have been made to understand the lipid remodeling pathways and to design anti-cancer drugs targeting the enzymes of eicosanoid biosynthesis. The function of histone H4 gene promoter (H4GP) in the repopulating pachytene spermatocytes (RPS) was investigated. Analysis of qualitative data collected through semi-structured interviews revealed that the majority of the participants recognised the existence of role overlap as inevitable within collaborative health care and felt it was of benefit to patients. The Cardiovascular Health Study of 5,888 older adults, was followed up to 9 years.

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More recently, adipocytokine which are linked to insulin resistance, low grade inflammation, endothelial dysfunction and vascular damage have been proposed as additional molecules able to modulate kidney function. Transforming growth factor-beta1 (TGF-beta 1) is a multifunctional cytokine that contributes to arterial remodelling by stimulating vascular smooth muscle cell (SMC) growth and collagen synthesis at sites of vascular injury. Erratum: Psychiatric Characteristics of the Cardiac Outpatients with Chest Pain. The data have been updated by an analysis of recent publications, according to the same methodological criteria as those used in the tenormin 25 mg tablet reference books: sample size, quality of questionnaire and statistical methods. Earlier open-label clinical trials have provided conflicting data on the effects of cyclosporin-A (CsA) on the clinical course and immune status of patients with HIV disease.

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Patients with multiple myeloma requiring long-term dialysis: presenting features, response to therapy, and outcome in a series of 20 cases. Cases of symptomatic, undiagnosed LLL may exist in the population. How islet dysfunction develops is not well understood at the cellular level, partly owing to the lack of approaches to study single islets longitudinally in vivo Here, we present a noninvasive, high-resolution system to quantitatively image real-time glucose metabolism from single islets in vivo, currently not available with any other method. To investigate the viscoelastic changes of the human cornea induced by riboflavin/UV-A cross-linking using Atomic Force Microscopy (AFM) at the nano level. Bipolar disorder is characterized by progressive changes in cognition with declines in executive functioning, memory and sustained attention. The geometric irregular tumour phantom with its inherent reference contours was an important tool for testing of different delineation methods and for teaching delineation. To establish reference range values for synovial fluid from clinically normal New World camelids. Massage improves growth quality by decreasing body fat deposition in male preterm infants. mansoni infections and MBL2 promoter and variants LY and LL increased susceptibility to S. Down-regulation of Nox2 in C2C12 cells by shRNA prevented insulin resistance induced by high glucose or palmitate but not H2O2.

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