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Amiodaron (Amiodarone)
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Amiodaron

Amiodaron is one of the most commonly used anti-arrhythmic drugs. While the United States FDA has labeled Amiodaron for the treatment of life-threatening ventricular arrhythmias. Amiodaron is commonly used off-label to treat supraventricular tachyarrhythmias such as atrial fibrillation as well as for the prevention of ventricular tachyarrhythmias (VTs) in high-risk patients.

Other names for this medication:
Amidrone, Amiocar, Amiodar, Amiodaron, Amiodarona, Amiodarone, Amiodaronum, Amiodura, Amiokordin, Amirone, Ancaron, Angoten, Aratac, Asulblan, Atlansil, Cardilor, Cardiodarone, Cardiron, Cordalin, Cordan, Coronal, Coronax, Coronovo, Escodaron, Eudarona, Kendaron, Keritmon, Miocor, Miodar, Mioritmin, Nexterone, Nodis, Novarona, Opacorden, Pacerone, Rithmik, Ritmocardyl, Rivodarone, Sedacoron, Tiaryt, Trangorex

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Also known as: Amiodarone

Description

Amiodarone is used to treat life-threatening heart rhythm problems called ventricular arrhythmias. This medicine is used in patients who have already been treated with other medicines that did not work well.

Amiodarone belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep your heart rhythm normal.

This medicine is available only with your doctor's prescription.

Dosage

Amiodaron is best taken with food. However, it is more important to take it consistently with regard to meals. If you take it with food, try to always take it with food to improve absorption of this medicine. If you prefer to take it on an empty stomach, then always try to take it on an empty stomach. If you want to achieve most effective results do not stop taking Amiodaron suddenly.

Overdose

If you overdose Amiodaron and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiodaron are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of amiodarone injection in the pediatric population. Safety and efficacy have not been established.

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Anaerobic digestion of crude glycerol as sole substrate in mixed reactor. The type of onset of stuttering was not related to the presence or absence of a family history of stuttering. This approach was applied to the qualitative analysis of the different samples of coptis chinensis, and the clustering result of samples was all highly consistent with the real situation. Analysis of capsular bags from donor eyes that had received an intraocular lens (IOL) revealed the presence of endogenous active TGF-beta2, matrix wrinkling, and expression of transdifferentiation markers alphaSMA and fibronectin. They also indicate that sCD14 may have an important role in potentiating responses to LPS in cells lacking mCD14. A treatment of the cultures by cantharidin, the protein phosphatase 2A inhibitor, resulted in massive induction of anthraquinone accumulation in the transgenic cultures only. As neuropsychological and neuroimaging studies have implicated different brain networks in the processing of action verbs and concrete nouns, the present study was aimed at contrasting reaction times to early and later-acquired action verbs and concrete nouns, in order to determine whether effects of word learning age express differently for the two types of words. To make an early diagnosis of ocular cicatricial pemphigoid, biopsy and immunohistochemical analysis of conjunctiva should be performed in every case of persistent conjunctival inflammation. We have validated a new recombinant virus phenotypic assay for determining HIV-1 tropism using both plasma and cell samples from patients who are candidates for treatment with CCR5 antagonists. To describe our experiences with the adjunctive role and benefits of surgery for lung disease due to non-tuberculous mycobacteria (NTM), specifically addressing its indications and timing.

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Reliability of a method for evaluating porosity in denture base resins. Deficiency of ICC might be related to the pathogenesis of diabetic gastroenteropathy in humans. By electron microscopy, the cells lining the pseudo-ductules displayed features of immature or embryonic pancreatic acinar cells characterized by prominent nucleoli, marked decrease in rough endoplasmic reticulum with increase of free ribosomes, atypical zymogen granules and abundant microfilaments and microtubules. To demonstrate nerve regeneration after ligating and crushing of the right hypoglossal nerve, fluorescein isothiocynate conjugated cholera toxin-B subunit (CTb-FITC) was injected into the intact fiber of the left hypoglossal nerve, and the central side from the crushed region of the right hypoglossal nerve fiber. We review recent work (Briedt et al., 2011., 2012) on a new approach to the formulation and solution of the stochastic inverse parameter determination problem, i.e. The PhIGs website contains tools that allow the study of genes within their phylogenetic framework through keyword searches on annotations, such as GO and InterPro assignments, and sequence similarity searches by BLAST and HMM. The utility of such applications for diagnosis, prognosis and follow-up are illustrated here by a number of examples: feline AIDS resulting from FIV infection, Leukocyte Adhesion Deficiency in Irish setters, deep pyoderma in German shepherds, Immune-mediated Thrombocytopenia, canine Systemic Lupus Erythematosus and Leishmaniasis, Leukemia and Lymphoma. Observation of oscillatory magnetic order in the antiferromagnetic superconductor HoNi2B2C.

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The minimum DD to maximize production across adjacent lactations depended on parity. To identify which children with acute otitis media are at risk of poor outcome and to assess benefit from antibiotics in these children. The present experiment was designed to see the effect of anterior or posterior truncal vagotomy on the movement of anterior and posterior walls of the stomach with the use of electromyography and force transducer. Epithelial sodium channel regulated by aldosterone-induced protein sgk. In addition, the fluorescence life of the FITC is extended from several days to several weeks with Evans blue. Milrinone was injected intracisternally (0.1 mg, 0.47 mmol/L) or intra-arterially (0.3 mg/kg, 1.2 mmol/L), and angiograms were performed 30, 60, 120, 180, 240, 300, and 360 minutes later on day 7. Air Pollution Exposure Distributions within Adult Urban Urban Populations in Europe. In this article, we propose a novel latent curve model (LCM) for studying the dynamic change of multivariate manifest and latent variables and their linear and interaction relationships. Clotting during autologous hematopoietic progenitor cells collection. To provide the underlying physical mechanism for formations of spatial- and polarization-entangled lasing patterns (namely, SPEPs), we performed experiments using a c-cut Nd:GdVO(4) microchip laser with off-axis laser-diode pumping.

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Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates. The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo. The collagen gland of Mytilus galloprovincialis: an ultrastructural and cytochemical study on secretory granules. Responsibilities of scientists and engineers: theory and practice. Thus, a comprehensive analysis to clarify the relative contributions of TIM gene family members in tumor progression may elucidate immunosurveillance systems in cancer patients.

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The learning set consisted of 1168 organic compounds with experimental data taken from the literature after critical evaluation. Anaphylactoid reactions in connection with infusion of invert sugar solutions are due to macromolecular contaminants. Transverse 3D true FISP MR arthrography images are useful for the difficult diagnosis of glenohumeral cartilage lesions and suitable for detecting labral abnormalities. In the nervous system, HGF plays a role as a potent neurotrophic and angiogenetic factor. We have constructed green fluorescent fusion proteins (GFP) using full-length (PKG-GFP) and truncations encoding either the regulatory domain of PKG1alpha (G1alphaR-GFP) or the catalytic domains of PKG1alpha (GFP-G1C) to examine the enzymatic properties and intracellular location. Our present cases suggest that 1) PEHO syndrome is not limited to Finnish heritage, and that 2) many more patients with PEHO could be identified with increased knowledge of the syndrome. The current study was undertaken to develop background data for a large chemical manufacturing company with emphasis on differentials in mortality associated with preselection factors, socioeconomic status, and general job categories. This reflects IL-21-mediated down-regulation of the BLyS receptor TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor) on GC B cells, thus limiting their capacity for BLyS binding and retention. A previously healthy 27-year-old man presented with 2 months of severe headaches and photophobia.

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Bacillus Calmette-Guerin immunotherapy appears to be more effective than other modalities in the treatment of renal adenocarcinoma. Diagnosis and extent of disease prior to stem cell rescue may have an impact on outcome. HER2-neu positivity in patients with small and node-negative breast cancer (pT1a,b,N0,M0): a high risk group?. Histopathological analysis of a needle biopsy specimen of the left cerebellar peduncle revealed diffuse gliosis in the presence of symmetrically distributed areas of demyelination. In the absence of flap dislocation, the finding of striae alone was subtle and went undetected initially. Trichothiodystrophy (TTD) is an autosomal recessive disorder characterized by brittle hair with reduced sulphur content, and mental and physical retardation. Delirium, the primary outcome, was assessed daily until discharge. Although rare, this diagnosis should be considered when a child presents with a solitary intramedullary tumor since its total resection can be achieved improving surgical outcome.

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We explored perceptions of the safety and side effects of oral and injectable hormonal contraceptives among low-income women at high risk of unintended pregnancy. We searched the Cochrane Stroke Group Trials Register (September 2013), MEDLINE (1966 to September 2013), EMBASE (1980 to September 2013) and Index to Scientific and Technical Proceedings (ISTP) (1980 to September 2013). Hence this study is investigating the role of ADMA in the progression of kidney injury and its circulatory status in Asian Indians with and without diabetic nephropathy. Reward value and uncertainty are represented by dopamine neurons in monkeys by distinct phasic and tonic firing rates. Taken together, these data strongly suggest that CD81 is a critical regulator of neuron-induced astrocytic differentiation. Inflammation on MRI is not only present in clinically swollen but also in non-swollen joints.

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A gene encoding the antimicrobial peptide, lactococcin K, was isolated from Lactococcus lactis subsp. In normal rats, net absorption and lumen to mucosa flux of zinc, normalized for differences in size of the intestine (mumol/h/g dry weight) were significantly greater in all perfused segments of the suckling compared with corresponding segments of the adolescent rats (p less than 0.05). This 70-year-old woman presented an ophthalmologist with progressive left-sided exophthalmos over the previous 2 months. Cerebral and extracerebral insufficiency in patients with poor prognosis of surgical treatment of cerebrovascular circulation disorders of hemorrhagic type. The treatment and outcome of a patient with sickle cell trait and metastatic renal medullary carcinoma is described. We also provide information concerning bacterial-host interactions and the mechanisms implicated in the pathogenesis of each of these extragastric diseases. Time-resolved continuum-edge-shift measurements in laser-shocked solids. Thus, regulation of cyclic nucleotide signalling is properly regarded as a composite of multiple component pathways involved in diverse aspects of tumour cell function.

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Proliferation and differentiation of the mammary gland does not explain this phenomenon, as shown by the relative ineffectiveness of perphenazine, a potent mitogenic and differentiating agent. The DNA sequences that are recognized by specific ligand molecules as studied by NMR are annotated in a figure to provide a clear view of target selection. With TRB3 gene silencing, protein levels of IRS-1, GLUT4 and p-AMPK were significantly increased in adipocytes. Use of antiretroviral therapy by intravenous drug users with HIV. The Anorectic Behaviour Observation Scale (ABOS) was designed to obtain information from relatives about behaviours and attitudes of patients with eating disorders (ED). These findings reinforce a growing consensus in the literature that, despite initiation perhaps some milliseconds after onset of the contralateral stimulus, there is a substantial delay, i.e., in the tens of milliseconds, before maximal suppression is achieved. In vitro induction of cytochrome P450 2B1- and 3A1-mRNA and enzyme immunostaining in cryopreserved precision-cut rat liver slices. Tryptanthrin was also found to suppress the VEGFR2-mediated ERK1/2 signalling pathway in HMEC-1 cells and molecular docking simulation indicated that tryptanthrin could bound to the ATP-binding site of VEGFR2.

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The authors examined risk factors for late-life suicide on the basis of general information collected directly from older subjects participating in a community-based prospective study of aging, the Established Populations for Epidemiologic Studies of the Elderly. NMDA-Receptor Antagonist Prevents Measles Virus-induced Neurodegeneration. For example, we are still unclear as to the potential benefit of polyunsaturated margarine over butter or olive oil. Using retention coefficients to predict the retention time of each peptide, several peptides in each protein set were found that exhibited anomalous behavior (i.e. As a result, primary care physicians sometimes struggle with questionnaire design and interpretation. Study size was calculated from the standard deviation (SD) of repeatability.

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As expected, we found that aging was associated with poorer spatial memory and reduced resting CBF. Salivary alpha-amylase and noradrenaline responses to corticotropin-releasing hormone administration in humans. The t-PA promoter is cAMP-responsive, and induction of t-PA gene transcription by EETs correlated with increases in intracellular cAMP levels and, functionally, with cAMP-driven promoter activity. Previous meta-analyses estimate that low-volume alcohol consumption protects against coronary heart disease (CHD). Due to the hemolytic nature of SCA, hemolysis represents an interesting therapeutic target for heme-scavenging purposes. Cyclosporine (CsA) and tacrolimus are inhibitors and substrates of the pump, and can induce its expression. There is also a law granting certain supports and services to those people who are considered to be in need of having someone to speak for them. Clinicians should screen patients with myofascial face pain for the presence of widespread pain, since this comorbid symptom pattern may be a contraindication for the use of oral splints. We describe a 32-year-old man with chest pain and a giant right atrial diverticulum who underwent surgical resection.

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PAX2/5/8 expression was surveyed in E16.5 male urogenital sinus (UGS) by RT-PCR. Hence, to promote understanding of the fine-grained dynamics of team learning, research should account for the temporal patterns of team learning behavior. Genomics of chronic lymphocytic leukemia microRNAs as new players with clinical significance. This convergence of evidence has led to the view that spatial memory, and the neurological structures associated with it, have been selected in niches that require memory for the location of goal objects. Strong evidence is emerging that mitochondrial permeability transition (MPT) may be important in certain physiological conditions and, above all, in the processes of cell damage and death. Townes-Brocks syndrome (TBS) is an autosomal dominant disorder with multiple malformations and variable expression.

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The research into levonorgestrel and ethinyl estradiol birth control pills the Drosophila melanogaster sex-determining system has been at the basis of all further research on insect sex determination. The survival of Escherichia coli O157:H7 in slurry from cattle fed different diets. Air pulse stimulation in rats is a simple, reliable, and effective way to determine laryngopharyngeal STs in rats and can be used as an efficient and affordable method for experimentation involving laryngeal sensory disorders. Anaerobic degradation of protocatechuate (3,4-dihydroxybenzoate) by Thauera aromatica strain AR-1. This perspective is juxtaposed with a popular vantage point of this stress hormone or of stress exposure that emphasizes the deleterious consequences or problems of this hormone. This case, and a re-evaluation of the literature, suggests that cases of cutaneous mucinosis of infancy that are not hamartomatous conditions such as mucinous naevi are in fact the infantile presentation of lichen myxoedematosus (papular mucinosis) and, in addition to other cases in the literature, suggests a genetic and familial factor in lichen myxoedematosus (papular mucinosis). Enhanced depth imaging optical coherence tomography of choroidal metastasis. Types of right bundles branch block and their clinical significance. The aim of this study was to investigate the gingivitis and periodontitis as a risk factor for stroke in Iranian population.

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Comparison of productivity of different vitamin green technologies under the space station conditions. Time-compressed versions of the WIPI and PB-K 50 speech discrimination measures were presented at two sensation levels to 60 children divided into three age-groups of 20 each. Similarly, mechanical stimulation of the spinal viscoelastic tissues excites the muscles with higher excitation intensity when more than one tissue (ligaments and discs for example) is stimulated. AXOS had no statistically significant effect on the range of gastrointestinal symptoms, except for a mild increase in flatulence. Neuropilins are highly conserved single pass transmembrane proteins specific to vertebrates.

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The aim of this study was to compare, in a large all-comer registry, the long-term clinical outcomes after percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for ostial/mid-shaft lesions versus distal bifurcation lesions in unprotected left main coronary artery (ULMCA) stenosis. Crude 1-month mortality was higher in patients with previous BAV. In addition, a panel of monoclonal and polyclonal antibodies was used to characterize the composition of the inflammatory infiltrate. Diffraction haloes resulting from corneal oedema and epithelial cell size. Kernicterus at low levels of serum bilirubin: the impact of bilirubin albumin-binding capacity. The morphologic evaluation of adhesive activity of human thrombocytes using both vital dye of cells and registration of adhesion process with fluorescent microscope is proposed. Spectroscopic results revealed that the formation of hydrogen-bonded aggregates involving carboxylic acid and pyridine nitrogen (acid-pyridine aggregates) between neighboring molecules in the melt state impedes crystallization, while the presence of carboxylic acid dimers (acid-acid dimers) in the melt favors crystallization.

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The impact of physician-performed ultrasonography on subsequent MRI and other outcomes of patients with shoulder disorders from January 2011 through October 2011 was determined using automated administrative and clinical data. A few complex systems have been proposed that are expected not to thermalize because their dynamics are integrable. They also support the hypothesized relation between changes in the timing of activity of the vastii and PFPS and provide the theoretic rationale to support physiotherapy treatment commonly used in the management of PFPS. Pb Glc6PD is 950 amino acids long with significant sequence similarity in both the devb and Glc6PD domains with the P. In countries using acellular vaccines, waning immunity is at least part of the problem. Initially it was discovered by bioassay-guided RP-HPLC-fractionation of culture extracts of Chondromyces robustus, strain Cm a13. Conventional smear technique should be used for FNA of nonmetastatic lymphoid lesions. Xanthohumol, a hop-derived prenylated flavonoid, promotes macrophage reverse cholesterol transport.

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One gene, multiple alleles: insights into the microevolution of pigmentation polymorphisms. Insulin-like growth factor I secreted from prostate stromal cells mediates tumor-stromal cell interactions of prostate cancer. The method is also applied to a more challenging data set that has had an artificial random error included. Thirty-two families with nocturnal enuresis/incontinence (one with four, 25 with three and six with two generations) were included. A total of 252 age matched consecutive patients were recruited from the endoscopy services in Leeds how much is zovirax tablets and Tokyo. As for cyclin E, its expression was higher with thymidine treatment than with sodium n-butyrate, particularly in nuclei.

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IL-8 production and expression were also investigated using immunocytochemistry and a reverse transcription-polymerase chain reaction method. The latter two are structurally similar and are different from the former two. The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. To elicit response endorectal stimulation of the pudendal nerve was delivered just to the left then right of the ischiatic spine using an electrode. On the basis of these data, alloxan diabetes is not transmissible in Yucatan pigs in the same way that theophylline tablets strength it is in rats. The value of early postoperative bone scan in slipped capital femoral epiphysis. Endoperoxides generated by activation of endothelial cyclooxygenase may be the endothelium-derived contracting factor(s) released in regenerated endothelium by lower concentrations of the peptide.

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The development of type 2 diabetes is linked to insulin resistance coupled with a failure of pancreatic beta-cells to compensate by adequate insulin secretion. Hysteretic spin crossover in iron(II) complexes of a new pyridine-triazole-pyrazine ligand is tuned by choice of NCE co-ligand. This article provides an overview of the ACO model and its role in the current policy context, highlights the key elements that will be common to all ACOs, and provides details of several challenges that may arise throughout the implementation process, including a host of technical, legal, and operational challenges. Urothelial papilloma: a rare cause of gross haematuria in childhood. The binding site of the antibody was studied by using N-terminal half and C-terminal half of midkine, both of which were chemically synthesized. Lethal Giant Lineage Tracing: Mutating Locally, Acting Globally. The histoenzymologic tests (such as those that demonstrate the ATP-ase and SDH-ase activity) are very useful for early detection of the structural and biochemical changes within the actinic keratosis lesion. Drugs and autoimmunity--a contemporary review and mechanistic approach. Because to our knowledge this gene has never been examined for alterations in humans, we evaluated whether mutations of HOXA10 are associated with cryptorchidism in humans.

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DH KA lesion on the other hand had no effect on the EB-induced LH increase. An increased anxiety-like behaviour was shown in MS360 rats at weaning, whereas a decreased anxiety response was found at 9 weeks of age compared with control rats. Hippocampal atrophy disrupts transfer generalization in nondemented enalapril dose equivalent to lisinopril elderly. Patients with history of tramadol abuse and intoxication were prospectively studied during a 3-year period. Not all patients who undergo splenectomy for idiopathic thrombocytopenic purpura (ITP) respond to operation. Analytical calculations excluded the possibility that the tissue was stimulated by changes in dissolved gas concentration, pH or temperature of the culture medium through compression of the gas phase. Cardiovascular morbidity and mortality seem to be increased in ankylosing spondylitis, perhaps as the result of biological inflammation and consecutive dyslipidemia. In vivo and in vitro effect of sulfathiazole on serum glycoproteins. In contrast to the wild-type ACE, the cleavage of ACE(NQ) was not blocked by the metallosecretase inhibitor batimastat but by the serine protease inhibitor, 1,3-dichloroisocoumarin.

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PID at the embryonic level, i.e., trophectoderm biopsy of blastocysts, is possible in centers with proven expertise in reproductive medicine and human genetics. In this study we investigated the role of COX in the capsaicin (Cap)-induced apoptosis in SK-N-SH human neuroblastoma cells. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. Coated vesicles in the rat adrenal glomerular zone after a low-sodium diet. A single R166G replacement produced by site-directed mutagenesis demonstrated that this change produced a nearly nonfunctional cytochrome c(1), with diminished growth on glycerol medium and diminished respiration but with the normal or near normal level of cytochrome c(1) having an attached heme group. We describe a rare case of bilateral LDD with cerebellar ectopia and presyrinx spinal cord changes. The loss in impulse due to the shorter force production time with the same take-off force is compensated with the increase in lift force, resulting in a higher vertical velocity (V(v)) than is expected from the conventional calculation of V(v) from the force impulse. Web alert: involving patients and the public in health service development and research.

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