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Amoxi (Amoxicillin)

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Amoxi is a penicillin-like (beta-lactam) antibiotic. It belongs to the most widely-used group of antibiotics available. Amoxi is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics.

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Also known as: Amoxicillin


Amoxi (amoxicillin) is a penicillin antibiotic that fights bacteria.

Amoxi is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.

Amoxi is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).


Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants older than 3 months, Children, and Adolescents: 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Neonates and Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours.


In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amoxi are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amoxi.

Crystalluria, in some cases leading to renal failure, has also been reported after Amoxi overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amoxi crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amoxi. Amoxi may be removed from circulation by hemodialysis.


Store this medicine at room temperature, away from heat, light, and moisture.

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