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Zofran (Ondansetron)

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Zofran is used to prevent nausea and vomiting caused by cancer medications (chemotherapy), radiation therapy, or surgery. It's available in different forms which can be helpful if you're unable to swallow or keep things down.

Other names for this medication:
Acidom, Domar, Doran, Emeset, Emitus, Emtop, Lupisetron, Naucid, Odanse, Omcet, Ondansetron, Ondar, Ondeo, Ondet, Onsett, Ontron, Onzil, Osetron, Pantorex, Ranidom, Ranon, Renol, Renty, Sanron, Supracetron, Tiron, Vomicare, Vomikind, Vomipra, Vomizen, Vorast, Voset, Xondmet, Zonda, Zondan, Zonde

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Also known as: Ondansetron


Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting.

This medicine is available only with your doctor's prescription.


Follow all directions on your prescription label. Do not take Zofran ODT in larger or smaller amounts or for longer than recommended.

Zofran ODT can be taken with or without food.

The first dose of ondansetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully.

Take the Zofran ODT regular tablet with a full glass of water.

To take the orally disintegrating tablet (Zofran ODT):

Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet. Use dry hands to remove the tablet and place it in your mouth. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.

To use Zofran ODT soluble film (strip) (Zuplenz):

Keep the strip in the foil pouch until you are ready to use the medicine. Using dry hands, remove the strip and place it on your tongue. It will begin to dissolve right away. Do not swallow the strip whole. Allow it to dissolve in your mouth without chewing. Swallow several times after the strip dissolves. If desired, you may drink liquid to help swallow the dissolved strip. Wash your hands after using Zuplenz.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Store at room temperature away from moisture, heat, and light. Store liquid medicine in an upright position.

Detailed Zofran ODT dosage information


Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.


Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the unused soluble film in the foil pouch until you ready to use it.

Detailed Zofran dosage information

Side effects

The most common side effects associated with Zofran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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A recently introduced tricuspid annuloplasty ring, the MC(3) ring, has a 3-dimensional form that is designed to remodel the tricuspid valve annulus. In general, the effects of EPR on the work circumstances of nursing staff are expected to be negative. The aim of the present study was to assess the potential involvement of acute changes in leptin concentrations following laparoscopic adjustable silicone gastric banding (LASGB). Reaming of the medullary cavity and its effect on diaphyseal bone. Two genomic DNA probes, pDK10 and pDK20, previously developped in Tunisia, were here applied to a collection of 41 isolates obtained from Algerian patients having cutaneous or visceral leishmaniases. We sought to study this association using objective measures of physical function and pulmonary function. Electronic absorption, CD, and magnetic CD (MCD) data collected for Ni-NCC are consistent with a diamagnetic Ni(II) center bound in square-planar geometry. A large number of naturally occurring mutations of the human AR gene have provided important information about AR molecular structure and intermolecular interactions. The differential effect played by adult and elderly actor primes was lost when static grasping hands (Control Study 1) and reach-to-grasp movements with uniform kinematic profiles (Control Study 2) were used. Effect of combined exposure to noise, vibration, and high temperatures on sympathico-adrenal system in sailors.

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Thin bipolar leads: a solution to problems with coaxial bipolar designs. This effect is explained in terms of apomorphine having a greater intrinsic activity and agonist affinity for striatal dopamine receptors than dopamine itself. Recent evidence suggests that the hepatic expression of heme oxygenase-1 (HO-1) may preserve hepatocellular integrity after hemorrhagic shock and resuscitation (HR). The most frequently observed aberrations were dicentric chromosomes, which were shown to be true dicentrics by examination by in situ hybridization with telomeric sequences. Imaging nonequilibrium phonon-induced backscattering in the quantum Hall regime. These injuries are associated more often with penetrating trauma rather than blunt trauma injury. It also amplified heavy ion radiation-elicited intracellular ROS generation, which induced ROS-sensitive ERK/MKP-1/caspase-3 activation in HMy2.CIR cells. The alternative use of 1a compared to Bis results in polyacrylamide gels with larger pore sizes and a broad pore size distribution. Future perspectives of circulating tumor DNA in colorectal cancer.

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Biosynthesis of AgNPs using aqueous leaf extract of Ipomoea eriocarpa and their anti-inflammatory effect on carrageenan-induced paw edema in male Wistar rats. Heparin-induced skin lesions vary from allergic reactions like erythema, urticaria, eczema to intradermal microvascular thrombosis associated with heparin-induced thrombocytopenia. A total of 21 patients with stenoses of the external carotid artery were investigated with a DE-CTA and CE-MRA before undergoing carotid angioplasty. Stronger associations at certain levels of income would have implications for underlying mechanisms. Between January 2000 and December 2004, we received 621 isolates of H.

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Anomalous behavior of the flux line lattice of vibrating high-Tc superconductors at 30 K in magnetic fields parallel to the CuO2 planes. To evaluate the role of Vitamin D deficiency in the etiology of hypocalcemic seizures in infancy. High-pressure Raman spectroscopy, EXAFS, X-ray diffraction, and optical absorption are discussed as methods for studying these transformations in CdSe, CdS, and Si nanocrystals. Strategically combining these two concepts could provide enhanced acceleration and efficiency. Prevention of post-operative pediatric tracheotomy wounds: A multidisciplinary team approach. Normal reticuloendothelial system (morphological entity or functional status of the connective tissue)?.

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Effect of Glutathione on the Taste and Texture of Type I Sourdough Bread. In the past 40 years there has been an evolution in metallurgy, biomechanics, and implant design for fracture fixation in the hand and wrist, quite unlike any other anatomic location in the body. Studies on selective genotyping have been limited to single-locus scenarios. The migration and invasion capability of HLaC 78 was enhanced by hMSC. We attribute this racial variation in the effect of incarceration to the high degree of racial neighborhood inequality in the United States: because white offenders generally come from much better neighborhoods, they have much more to lose from a prison spell. Breath hydrogen (H2) analysis was utilized to determine whether intestinal absorption of carbohydrate might decline with age.

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The technique that seems most likely to satisfy all of these requirements is the multiplexed suspension (bead-based) assay, which offers a number of advantages over alternative approaches such as ELISAs and microarrays. Five angular and three linear measurements were created from these landmarks and planes. In this study, we analyzed the role of this pathway during insulin-like growth factor II (IGF-II)-induced myoblast differentiation. This report represents a series of pathophysiologic studies performed for patients with cervicogenic headache and the results achieved by a new pharmacologic treatment for the disease. These data suggest that 1) KO of COX2 in podocytes does not ameliorate diabetic kidney disease in Akita mice, and 2) some basal level of podocyte COX2 expression in podocytes is necessary to attenuate the adverse effects of diabetes on glomerular filtration barrier function. Refractive consequences of corneal transplants are analyzed using corneal biomechanical models assuming homogeneous and inhomogeneous stiffness distributions across the cornea. Despite a high rate of early revascularization and use of intra-aortic balloon pump counterpulsation therapy, the prognosis of patients with cardiogenic shock has remained poor. A diurnal rhythm of retinal melatonin was found to persist after pinealectomy in both experiments. Carbon isotope discrimination (delta) was reduced primarily by salinity. Excluding these four subjects, those with residual urine were slightly older than the others (P less than 0.05), but the known duration of diabetes was increased only for the insulin-dependent group (P less than 0.05).

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Synaptic Activation of GABAA Receptors Causes a Depolarizing Potential Under Physiological Conditions in Rat Hippocampal Pyramidal Cells. These findings are consistent with the premise that the T2 abnormality depicts the area at risk, a zone of reversibly and irreversibly injured myocardium associated with reperfused subendocardial infarctions. We administered four increasing doses: 5, 25, 50 and 100 mg/ml acetylsalicylic acid (ASA) with saline solution control. The Father Focused Referral (FFR) sample included 12 children whose father was unavailable to them. However, while studies of latent structure have yielded valuable information about disorder boundaries, their reliance on non-representative samples and failure to evaluate the practical implications of structural findings has limited their ability to effect nosological change.

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Many-hour stimulation of the mentioned structures also produced stable famciclovir 500 mg arterial hypertension in adrenalectomized rabbits if preceded by the administration of hydrocortisone together with adrenaline. The duplication of an IS50 element suggests the occurrence of a replicative mechanism of transposition. Estimators are obtained for the ratio of restitution and induction processes involved in the origin of chromosomal aberrations. Inhibition of Stat3 expression and phosphorylation by short interfering RNA or Cucurbitacin I resulted in the loss of collagen production, impaired proliferation and delayed cell migration in KFs. After total systemic heparinization (3 was obtained for cardiopulmonary bypass, a multiplane TEE probe was inserted without difficulty to monitor myocardial contractility during weaning from CPB. In Turkey, especially among cancer patients, there is a high prevalence of complementary and alternative medicine (CAM) usage and the most commonly used form of CAM is herbal medicines. Combined treatments utilizing aminoflavone in conjunction with paclitaxel or camptothecin may provide an even greater cytotoxic effect than achieved with aminoflavone alone. We present a general framework for finding the time-optimal evolution and the optimal Hamiltonian for a quantum system with a given set of initial and final states.

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Effect of thyrocalcitonin on calcium efflux in liver slices of rats. We show that a closed-form solution exists in the dual-space using a minimum of three views while a solution with two views is possible through the use of non-linear optimisation and object constraints on the size of the object shape. The incubation period in females was estimated to be shorter than that in males. The initiating event in preeclampsia has been postulated to be reduced uteroplacental perfusion as a result of abnormal cytotrophoblast invasion of spiral arterioles. Findings are discussed in terms of the rates of general psychological adjustment, internalizing behavior problems, externalizing behavior problems, social competence, correlates or predictors of adjustment, and quality of life among survivors. PIP scores were significantly correlated with a measure of state anxiety and also with parenting stress, demonstrating construct validity.

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Rising health care needs impose increased pressure on limited budgets of health care systems around the world. In the last years, it has been accumulated data about an important association between addictions and attention-deficit hyperactivity disorder (ADHD). Safeness of Simplex-tobramycin bone cement in patients with renal dysfunction undergoing total hip replacement. The other groups searched information mostly to update their knowledge. Intraindividual variability in positive and negative affect over 45 days: do older adults fluctuate less than young adults?. DEC effects on microfilariae depend on inducible NO synthase (iNOS). Oral health status and treatment needs of pregnant women in Lagos State. Then goes the lymphocyte reaction with a following transformation of lymphocytes to blasts and their further differentiation and proliferation into young forms of cells of the plasmocyte row. Spontaneous reporting of adverse drug reactions (ADRs) is the basis of pharmacovigilance.

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Results of combined treatment in patients with cancer of the stomach: palliative gastrectomy, large-dose Mitomycin-C, and bone marrow transplantation. ARF1(Q71L) was mostly colocalized with betaCOP, but ARF5(Q71L) less so. In these situations, one should use clinical judgment to determine the need for further observation, CTA or catheter angiography, or surgical exploration. Apoptosis is a physiological form of cell death required to ensure that the rate of cell division is balanced by the rate of cell death in multicellular organisms. We selectively review recent experiments with rats in which systematic changes in information processing of new stimuli are observed after training with different stimuli. Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison zithromax 500 mg oral tablet with a laboratory strain K-12. This method relies on higher-order statistical analysis of temporal fluctuations (caused by fluorescence blinking/intermittency) recorded in a sequence of images (movie). Making an informed choice in the catering environment: what do consumers want to know?.

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Developing oocysts of the gregarine Pterospora floridiensis Landers 2001 were examined by transmission electron microscopy. The neutralizer was selected and be appraised by test of neutralizer. Effect of xanax overdose video medium-pressure UV-lamp treatment on disinfection by-products in chlorinated seawater swimming pool waters. The assay was validated for the determination of DX-8951 and UM-1 in human plasma and urine. Wine and olive oil, essential components of the Mediterranean diet, are considered important factors for a healthy life style. The rate of skin prick test positivity in asthmatics was significantly higher than that of the COPD patients. Ischemia preconditioning also decreased edema in the muscule layer and increased Chiu score in experimental rats. The titers of antibodies to desmoglein 3 and 1 were 118 and 25.9, respectively, by enzyme-linked immunosorbent assay. Can atrophy of the brain arise from prolonged inhalation of mineral turpentine?.

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Bluetongue virus (BTV) is an arthropod-borne virus transmitted by Culicoides species to vertebrate hosts. Focal liver lesions are routinely encountered by clinical radiologists and represent a wide spectrum of pathology. Whereas it was long known that high doses of oxidants may damage or kill cells, the effect of low doses or long-time exposure to small flux rates of oxidants have been the focus of the free radical research until now. His admission to hospital was soon followed by collapse and death. Our studies demonstrate that the relationship between maternal dose of methadone and the incidence of neonatal withrawal symptoms was closely related to the last maternal dose of methadone. The human herpesvirus 6 (HHV-6) early protein, p41, encoded by the U27 gene has been detected in oligodendrocytes of multiple sclerosis (MS) patients by using a monoclonal antibody (MAb to p41/38).

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